X-REPORT BREAST: IT TOOLS TO EARLY DETECT BREAST CANCER THROUGH OPTICAL IMAGING - Dynamic Optical Breast Imaging, DOBI

Fulvio Casali, Cinzia Mambretti, Silvia Bellini, Mirella Bernabò

2012

Abstract

Breast cancer is the second leading cause of cancer deaths in women today; according to the American Cancer Society, about 1.3 million women will be diagnosed with breast cancer annually worldwide and about 465,000 will die from this disease. In the western world, its incidence in females in premenopausal status results similar or superior to the incidence in females in postmenopausal status. Therefore, it is imperative to identify diagnostic tools able to detect breast cancer in young women from the very early stages. This paper presents an IT application developed to support Medical Doctors in diagnosing and reporting with an innovative non-radiating, non-invasive optically-based breast cancer detection system, suitable for scanning of young women. This system - ComfortScan - relies on a methodology – DOBI, Dynamic Optical Breast Imaging - based upon the use of a red monochromatic light beam and able to identify neoangiogenetic areas related to the onset of cancer. The application – X-Report Breast – interprets the images captured by ComfortScan and provides automatic reporting and diagnosis. X-Report Breast proves to be highly valuable in supporting the early diagnosis of breast cancers with ComfortScan, increasing the survival probability and diminishing the invasive surgical impacts.

References

  1. J. Ferlay, F. Bray, P. Pisani and D.M. Parkin. GLOBOCAN 2002. Cancer Incidence, Mortality and Prevalence Worldwide. IARC CancerBase No. 5, version 2.0. IARCPress, Lyon, 2004.
  2. American Cancer Society Breast Cancer Facts & Figures, 2005-2006
  3. Nass S. J., Henderson C., Lashof J. C., eds. Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer. Washington, DC: National Academy Press. 2001. Prepublication copy:16.
  4. Eliceiri B. P., Cheresh D. A. The role of av integrins during angiogenesis. Molecular Medicine 1998; 4:741.
  5. Angiogenesis Foundation, Understanding Angiogenesis, www.angio.org, April 2001.
  6. National Cancer Institute, Cancer Information, CancerNet, Types of Cancer, Breast Cancer www.nci.nih.gov, April 2001
  7. Angiogenesis Foundation, Understanding Angiogenesis, www.angio.org, April 2001
  8. Li W. W., Li V. W., Tsakayannis D., Casey R., Jaffe M., Atwater L. A., eds. Market Study and Analysis of Angiogenesis-Dependent Diseases. Cambridge, MA: Angiogenesis Foundation, 2001:17.
  9. Folkman J.: Tumor angiogenesis: therapeutic implications, New England Journal of Medicine 1971; 285:1182- 1186.
  10. Weinberg R. A., One Renegade Cell: How Cancer Begins. New York, NY: Basic Books. 1998:143-146.
Download


Paper Citation


in Harvard Style

Casali F., Mambretti C., Bellini S. and Bernabò M. (2012). X-REPORT BREAST: IT TOOLS TO EARLY DETECT BREAST CANCER THROUGH OPTICAL IMAGING - Dynamic Optical Breast Imaging, DOBI . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2012) ISBN 978-989-8425-91-1, pages 173-178. DOI: 10.5220/0003771401730178


in Bibtex Style

@conference{biodevices12,
author={Fulvio Casali and Cinzia Mambretti and Silvia Bellini and Mirella Bernabò},
title={X-REPORT BREAST: IT TOOLS TO EARLY DETECT BREAST CANCER THROUGH OPTICAL IMAGING - Dynamic Optical Breast Imaging, DOBI},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2012)},
year={2012},
pages={173-178},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003771401730178},
isbn={978-989-8425-91-1},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2012)
TI - X-REPORT BREAST: IT TOOLS TO EARLY DETECT BREAST CANCER THROUGH OPTICAL IMAGING - Dynamic Optical Breast Imaging, DOBI
SN - 978-989-8425-91-1
AU - Casali F.
AU - Mambretti C.
AU - Bellini S.
AU - Bernabò M.
PY - 2012
SP - 173
EP - 178
DO - 10.5220/0003771401730178