OPTICAL SPECTROSCOPY AND OBSTACLES BY NON-INVASIVE DETECTION OF GLUCOSE CONCENTRATION BY HOME MONITORING

O. Abdallah, Q. Qananwah, A. Bolz, J. Hansmann, H. Walles, T. Hirth

2012

Abstract

Tight glycemic monitoring and control is the main goal in successful diabetes management to avoid its complications. Frequent blood glucose measurements with a combination of regimented diet, exercise and insulin administration can accomplish this task. Different methods are applied for non-invasive measurement of blood glucose concentration. Despite the great interest and the intensive research in this field since 1980s, there is no convenient device at the market that can measure the glucose concentration non-invasively in an easy manner. This paper discusses the different methods for detecting the glucose concentration. Elastic and inelastic (Raman) scattering as well as fluorescence and IR Spectroscopy measurements well be shown and discussed for the development of a compact non-invasive device for home monitoring. In conclusions, an optical multi-sensor measuring the fluorescence and light scattering in the tissue optical window in and around visible range (360 nm – 1200 nm) taking the perturbation factors into account is promising and under development.

References

  1. Abdallah O., Qananwah Q., Bolz, A. A., Hansmann J., Hinderer S., and Mertsching H., 2011. Fluorescence Spectroscopy by Detection of Glucose Concentrations in DMEM-Solutions and its Perspectives for Noninvasive Measurement BIODEVICES 2011 part of BIOSTEC, The International Joint Conference on Biomedical Engineering Systems and Technologies, Rome, Italy
  2. Abdallah O., Hansmann J., Bolz A. and Mertsching H., 2010. "IR spectroscopy vs. Raman scattering by measurement of glucose concentration", Proc. SPIE 7376, 73760B; doi:10.1117/12.871469
  3. Barman Ishan, Chae-Ryon Kong, Gajendra P. Singh, Ramachandra R. Dasari, and Michael S. Feld, 2010: Accurate Spectroscopic Calibration for Noninvasive Glucose Monitoring by Modeling the Physiological Glucose Dynamics. Analytical Chemistry 2010, Vol. 82, No. 14, pp. 6104-6114
  4. Caduff, A., Talary, M., Mueller, M., Dewarrat, F., Klisic, J., Donath, M., Heinemann, L., Stahel, W., 2009. Noninvasive glucose monitoring in patients with Type 1 diabetes: A Multisensor system combining sensors for dielectric and optical characterisation of skin. Biosensors and Bioelectronics Vol. 24, pp. 2778- 2784.
  5. D'Auria, S., Herman, P., Rossi, M., Lakowicz, J., 1999. The Fluorescence Emission of the Apo-glucose Oxidase from Aspergillusniger as Probe to Estimate Glucose Concentrations. Biochemical and Biophysical Research Communications, Vol. 263, pp. 550-553.
  6. Evans, N., Gundi, L., Rolinski, O., Birch, D., Pickup, J., 2003. Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in Fibroblasts and adipocytes: A model for skin glucose sensing. Diabetes Technology & Therapeutics, Vol. 5, No. 5.
  7. Evans, N.D., Gnudi, L., Rolinski, O.J., Birch, D.J., Pickup, J.C., 2005. Glucose-dependent changes in NAD(P)Hrelated fluorescence lifetime of adipocytes and fibroblasts in vitro: Potential for non-invasive glucose sensing in diabetes mellitus. J. of Photochemistry and Photobiology B: Biology, Vol. 80, pp. 122-129.
  8. Gaster, Barak, Hirsch, MD; Irl B., MD, 1998. The Effects of Improved Glycemic Controlon Complications in Type 2 Diabetes, Arch Intern Med/VOL 158
  9. Harman-Boehm Ilana, Avner Gal, Alexander M. Raykhman, Jeffrey D. Zahn, Eugene Naidis, and Yulia Mayzel, 2009. Noninvasive Glucose Monitoring: A Novel Approach, Journal of Diabetes Science and Technology Volume 3, Issue 2
  10. Khalil, O.S., 2004. Non-invasive glucose measurement technologies: An update from 1999 to the dawn of the new millennium. Diabetes Technol. Ther., 6, 660-697
  11. Lakovics, J., 2006. Principles of Fluorescence. Springer.
  12. Maruo K., M. Tsurugi, J.Chin, T. Ota, H. Arimoto, Y. Yamada, M. Tamura, M. Ishii, and Y. Ozaki, 2003. "Noninvasive Blood Glucose Assay Using a Newly Developed Near-Infrared System," IEEE Journal Of Selected Topics In Quantum Electronics, 9 (2)
  13. Mezzetti Andrea, Cipollone Francesco, Cuccurullo Franco, 2000. Oxidative stress and cardiovascular complications in diabetes: Isoprostanesas new markers on an old paradigm, Cardiovasc. Research 47, 475- 488
  14. Moschou, E., Sharma, P., Deo, S., Daunert, S., 2004. Fluorescence Glucose Detection: Advances Toward the Ideal In Vivo Biosensor. Journal of Fluorescence, Vol. 14, No. 5.
  15. Pambianco Georgia, Tina Costacou, Demetrius Ellis, Dorothy J. Becker, Ronald Klein, andTrevor J. Orchard, 2006. The 30-Year Natural History of Type 1 Diabetes Complications: The Pittsburgh Epidemiology of Diabetes ComplicationsStudy Experience, DIABETES, VOL. 55
  16. Pickup, C. John, Faeiza Hussain, Nicholas D. Evans, Olaf J. Rolinski, David J.S. Birch: Review: Fluorescencebased glucose sensors, Biosensors and Bioelectronics 20, 2555-2565 (2005)
  17. Smith John L., 2011, The Pursuit of Noninvasive Glucose: “Hunting the Deceitful Turkey” Second Edition
  18. Tura Andrea, Stefano Sbrignadello, Domenico Cianciavicchia, Giovanni Pacini and Paolo Ravazzani, 2010. A Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions Sensors 10, pp. 5346-5358;
  19. Wang Chuji and Sahay Peeyush, 2009, Breath Analysis Using Laser Spectroscopic Techniques: Breath Biomarkers, Spectral Fingerprints, and Detection Limits, Sensors 2009, 9, PP. 8230-8262
  20. Yamakoshi, K. Y. Yamakoshi: Pulse Glucometry, 2006. A New Approach for Non-invasive Blood Glucose Measurement Using Instantaneous Differential Near Infrared Spectrophotometry, Journal of Biomedical Optics 11(5), 1-11
  21. Zierler, K., 1999. Whole body glucose metabolism. Am J Physiol, 276(3 Pt 1):E409-E426
Download


Paper Citation


in Harvard Style

Abdallah O., Qananwah Q., Bolz A., Hansmann J., Walles H. and Hirth T. (2012). OPTICAL SPECTROSCOPY AND OBSTACLES BY NON-INVASIVE DETECTION OF GLUCOSE CONCENTRATION BY HOME MONITORING . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012) ISBN 978-989-8425-89-8, pages 291-296. DOI: 10.5220/0003796902910296


in Bibtex Style

@conference{biosignals12,
author={O. Abdallah and Q. Qananwah and A. Bolz and J. Hansmann and H. Walles and T. Hirth},
title={OPTICAL SPECTROSCOPY AND OBSTACLES BY NON-INVASIVE DETECTION OF GLUCOSE CONCENTRATION BY HOME MONITORING},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)},
year={2012},
pages={291-296},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003796902910296},
isbn={978-989-8425-89-8},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)
TI - OPTICAL SPECTROSCOPY AND OBSTACLES BY NON-INVASIVE DETECTION OF GLUCOSE CONCENTRATION BY HOME MONITORING
SN - 978-989-8425-89-8
AU - Abdallah O.
AU - Qananwah Q.
AU - Bolz A.
AU - Hansmann J.
AU - Walles H.
AU - Hirth T.
PY - 2012
SP - 291
EP - 296
DO - 10.5220/0003796902910296