Exposome, Health and Biomedical Informatics - An Emerging Discipline and Its Interaction with Current Biomedical Informatics

Guillermo Lopez-Campos, Riccardo Bellazzi, Fernando Martin-Sanchez

2015

Abstract

In the last decade we have witnessed the raising of the exposome (the set of a life-long individual exposures) as an increasingly interesting area and discipline due to its relationship with health. These new approaches rely heavily in the use of different informatics related methods and are generating new data types that in the future should be handled by biomedical informatics. This position paper refers to some of the challenges that are related with these new approaches from a biomedical informatics perspective, describing the interactions with related disciplines such as bioinformatics, public health informatics and others. We discuss as well the role of the exposome in bringing new data types that might be handled by biomedical informatics in the context of Big and small data generated in this approaches and its relationship with the participatory medicine and how they could influence future health information systems. Finally, we consider that the current situation of the exposome resembles the early years of genomics, when it was clear that genomic information had a great potential for health and drove a discussion about how to better integrate and analyse the most relevant pieces of information for health purposes.

References

  1. Estrin, D., 2014. Small data, where n=me. Communications of the ACM, 57 :4, 32-34.
  2. Lind, P. M., Riserus, U., Salihovic, S., Bavel, B. & Lind, L. 2013. An environmental wide association study (EWAS) approach to the metabolic syndrome. Environ Int, 55, 1-8.
  3. Martin-Sanchez, F., Maojo, V. & Lopez-Campos, G. 2002. Integrating genomics into health information systems. Methods Inf Med, 41, 25-30.
  4. McAfee A, Brynjolfsson E., 2012. Big data: the management revolution. Harvard Business Review, 90:60-66, 68, 128.
  5. Nieuwenhuijsen, M. J., Donaire-Gonzalez, D., Foraster, M., Martinez, D. & Cisneros, A. 2014. Using personal sensors to assess the exposome and acute health effects. Int J Environ Res Public Health, 11, 7805-19.
  6. Nuwaysir, E. F., Bittner, M., Trent, J., Barrett, J. C. & Afshari, C. A. 1999. Microarrays and toxicology: the advent of toxicogenomics. Mol Carcinog, 24, 153-9.
  7. Patel, C. J., Bhattacharya, J. & Butte, A. J. 2010. An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. PLoS One, 5, e10746.
  8. Rappaport, S. M. 2012. Biomarkers intersect with the exposome. Biomarkers, 17, 483-9.
  9. Stahler, G. J., Mennis, J. & Baron, D. A. 2013. Geospatial technology and the "exposome": new perspectives on addiction. Am J Public Health, 103, 1354-6.
  10. Wild, C. P. 2005. Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. Cancer Epidemiol Biomarkers Prev, 14, 1847-50.
Download


Paper Citation


in Harvard Style

Lopez-Campos G., Bellazzi R. and Martin-Sanchez F. (2015). Exposome, Health and Biomedical Informatics - An Emerging Discipline and Its Interaction with Current Biomedical Informatics . In Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2015) ISBN 978-989-758-068-0, pages 580-584. DOI: 10.5220/0005278405800584


in Bibtex Style

@conference{healthinf15,
author={Guillermo Lopez-Campos and Riccardo Bellazzi and Fernando Martin-Sanchez},
title={Exposome, Health and Biomedical Informatics - An Emerging Discipline and Its Interaction with Current Biomedical Informatics},
booktitle={Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2015)},
year={2015},
pages={580-584},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005278405800584},
isbn={978-989-758-068-0},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2015)
TI - Exposome, Health and Biomedical Informatics - An Emerging Discipline and Its Interaction with Current Biomedical Informatics
SN - 978-989-758-068-0
AU - Lopez-Campos G.
AU - Bellazzi R.
AU - Martin-Sanchez F.
PY - 2015
SP - 580
EP - 584
DO - 10.5220/0005278405800584