A CASE-BASED DIALOGUE SYSTEM FOR INVESTIGATING THERAPY INEFFICACY

Rainer Schmidt, Olga Vorobieva

Abstract

ISOR is a Case-Based Reasoning system for long-term therapy support in the endocrine domain and in psychiatry. ISOR performs typical therapeutic tasks, such as computing initial therapies, initial dose recommendations, and dose updates. ISOR deals especially with situations where therapies become ineffective. Causes for inefficacy have to be found and better therapy recommendations should be computed. In addition to former already solved cases, ISOR uses further knowledge forms, especially medical histories of query patients themselves and prototypes. Furthermore, the knowledge base consists of therapies, conflicts, instructions etc. So, different forms and steps of retrieval are performed, while adaptation occurs as an interactive dialog with the user.

References

  1. Alacorn, R.D., Glover, S., Boyer, W., Balon, R., 2000. Proposing an algorithm for the pharmacological treatment of posttraumatic stress disorder. Ann Clin Psychiatry 12 (4) 239-246
  2. Barbee, J.G., Jamhour, N.J., 2002. Lamotrigine as an augmentation agent in treatment-resistant depression. J Clin Psychiatry 63 (8) 737-41
  3. Bichindaritz,I., 1994. A case-based assistant for clinical psychiatry expertise, Journal of the American Medical Informatics Association, Symposium Supplement 673- 677
  4. Cuffel, B.J., Azocar, F., Tomlin, M., Greenfield, S.F., Busch, A.B., Croghan, T.W., 2003. Remission, residual symptoms, and nonresponse in the usual treatment of major depression in managed clinical practice. J Clin Psychiatry 64 (4) 397-402
  5. Davidson, R.J., 1991. Cerebral asymmetry and affective disorders: A developmental perspective. In: Cicchetti, D., Toth, S.L. (eds.): Internalizing and externalizing expressions of dysfunction. Rochester Symp. on Developmental Psychopathology 2, Erlbaum, Hillsdale, 123-133
  6. DeGroot, L.J., 1994. Thyroid Physiology and Hypothyroidsm. In: Besser, G.M., Turner, M. (eds.): Clinical endocrinilogy, Wolfe, London, Chapter 15
  7. Expert Consensus Guideline Series Treatment of Posttraumatic Stress Dosorder, 2000. J Clin Psychiatry 60 (suppl 16) 1-76
  8. Flor-Henry, P., 1983. Cerebral Basis of Psychopathology. John Wright, Boston
  9. Gelder, M.G., Lopez-Ibor, U., Andeasen, N.C. (eds.), 2000. New Oxford Textbook of Psychiatry. Oxford University Press, Oxford
  10. Hampel, R., 2000. Diagnostik und Therapie von Schilddr├╝senfunktionsst├Ârungen. UNI-MED, Bremen
  11. Hirschfeld, R.M., Montgomery, S.A., et al, 2002. Partial response and nonresponse to antidepressant therapy: current approaches and treatment options. J Clin Psychiatry 63 (9) 826-37
  12. Kalinowsky, L., Hippius, H., 1969. Pharmacolological, convulsive and other somatic treatments in psychiatry. Grunee&Stratton, New York London
  13. Keitner, G.I, Posternak, M.A., Ryan, C.E., 2003. How many subjects with major depressive disorder meet eligibility requirements of an antidepressant efficacy trial? J Clin Psychiatry 64 (9) 1091-3
  14. Lam, R.W., Wan, D.D., Cohen, N.L., Kennedy, S.H., 2002. Combining antidepressants for treatmentresistant depression: a review, J Clin Psychiatry 63 (8) 685-93
  15. Leonhard, K., 1979. The Classification of the Endogenous Psychoses. John Wiley, New York
  16. Ma, J., Knight, B.A., 2003. Framework for Historical Case-Based Reasoning. In: Proc ICCBR-2003, Springer, Berlin, 246-260
  17. Marling, C., Whitehouse, P., 2001. Case-Based Reasoning in the care of Alzheimer's disease patients. In: Proc ICCBR-2001, Springer, Berlin, 702-715
  18. Osser, D.N., Patterson, R.D., 1998. Algorithms for the pharmacotherapy of depression, parts one and two. Directions in Psychiatry 18, 303-334
  19. Schmidt, R., Gierl, L., 2001. Case-based Reasoning for Antibiotics Therapy Advice: An Investigation of Retrieval Algorithms and Prototypes. Artificial Intelligence in Medicine 23 (2) 171-186
  20. Stein, M.B., 2003. Attending to anxiety disorders in primary care. J Clin Psychiatry 64 (suppl 15) 35-39
  21. Tucker, D.M., Liotti, M., 1989. Neuropsychological mechanisms of anxiety and depression. In: Boller, F., Grafman, J. (eds.): Handbook of Neuropsychology, vol. 3. Elsevier, Amsterdam, 443-456
  22. Tversky, A., 1977. Features of similarity. Psychological review 84, 327-352
  23. Vorobieva, O., Gierl, L., Schmidt, R., 2002. Case-based Adaptation in Medicine - Focusing on Hypothyroidism. In: Proc UK-Workshop on CBR, University of Paisley Press, Paisley, 61-68
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Paper Citation


in Harvard Style

Schmidt R. and Vorobieva O. (2007). A CASE-BASED DIALOGUE SYSTEM FOR INVESTIGATING THERAPY INEFFICACY . In Proceedings of the Second International Conference on Software and Data Technologies - Volume 1: ICSOFT, ISBN 978-989-8111-05-0, pages 171-178. DOI: 10.5220/0001323901710178


in Bibtex Style

@conference{icsoft07,
author={Rainer Schmidt and Olga Vorobieva},
title={A CASE-BASED DIALOGUE SYSTEM FOR INVESTIGATING THERAPY INEFFICACY},
booktitle={Proceedings of the Second International Conference on Software and Data Technologies - Volume 1: ICSOFT,},
year={2007},
pages={171-178},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001323901710178},
isbn={978-989-8111-05-0},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Second International Conference on Software and Data Technologies - Volume 1: ICSOFT,
TI - A CASE-BASED DIALOGUE SYSTEM FOR INVESTIGATING THERAPY INEFFICACY
SN - 978-989-8111-05-0
AU - Schmidt R.
AU - Vorobieva O.
PY - 2007
SP - 171
EP - 178
DO - 10.5220/0001323901710178