ONTOLOGY BASED INTEGRATION OF DISTRIBUTED AND HETEROGENEOUS DATA SOURCES IN ACGT

Luis Martín, Alberto Anguita, Víctor Maojo, Erwin Bonsma, Anca Bucur, Jeroen Vrijnsen, Mathias Brochhausen, Christian Cocos, Holger Stenzhorn, Manolis Tsiknakis, Martin Doerr, Haridimos Kondylakis

Abstract

In this work, we describe the set of tools comprising the Data Access Infrastructure within Advancing Clinico-genomic Trials on Cancer (ACGT), a R&D Project funded in part by the European. This infrastructure aims at improving Post-genomic clinical trials by providing seamless access to integrated clinical, genetic, and image databases. A data access layer, based on OGSA-DAI, has been developed in order to cope with syntactic heterogeneities in databases. The semantic problems present in data sources with different nature are tackled by two core tools, namely the Semantic Mediator and the Master Ontology on Cancer. The ontology is used as a common framework for semantics, modelling the domain and acting as giving support to homogenization. SPARQL has been selected as query language for the Data Access Services and the Mediator. Two experiments have been carried out in order to test the suitability of the selected approach, integrating clinical and DICOM image databases.

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Paper Citation


in Harvard Style

Martín L., Anguita A., Maojo V., Bonsma E., Bucur A., Vrijnsen J., Brochhausen M., Cocos C., Stenzhorn H., Tsiknakis M., Doerr M. and Kondylakis H. (2008). ONTOLOGY BASED INTEGRATION OF DISTRIBUTED AND HETEROGENEOUS DATA SOURCES IN ACGT . In Proceedings of the First International Conference on Health Informatics - Volume 1: Special Session on Knowledge Discovery and Decision Support Systems in Health Information Systems, (BIOSTEC 2008) ISBN 978-989-8111-16-6, pages 301-306. DOI: 10.5220/0001045503010306


in Bibtex Style

@conference{special session on knowledge discovery and decision support systems in health information systems08,
author={Luis Martín and Alberto Anguita and Víctor Maojo and Erwin Bonsma and Anca Bucur and Jeroen Vrijnsen and Mathias Brochhausen and Christian Cocos and Holger Stenzhorn and Manolis Tsiknakis and Martin Doerr and Haridimos Kondylakis},
title={ONTOLOGY BASED INTEGRATION OF DISTRIBUTED AND HETEROGENEOUS DATA SOURCES IN ACGT},
booktitle={Proceedings of the First International Conference on Health Informatics - Volume 1: Special Session on Knowledge Discovery and Decision Support Systems in Health Information Systems, (BIOSTEC 2008)},
year={2008},
pages={301-306},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001045503010306},
isbn={978-989-8111-16-6},
}


in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Health Informatics - Volume 1: Special Session on Knowledge Discovery and Decision Support Systems in Health Information Systems, (BIOSTEC 2008)
TI - ONTOLOGY BASED INTEGRATION OF DISTRIBUTED AND HETEROGENEOUS DATA SOURCES IN ACGT
SN - 978-989-8111-16-6
AU - Martín L.
AU - Anguita A.
AU - Maojo V.
AU - Bonsma E.
AU - Bucur A.
AU - Vrijnsen J.
AU - Brochhausen M.
AU - Cocos C.
AU - Stenzhorn H.
AU - Tsiknakis M.
AU - Doerr M.
AU - Kondylakis H.
PY - 2008
SP - 301
EP - 306
DO - 10.5220/0001045503010306