A NEW INSTRUMENTED BIOLOGICAL DEVICE DESIGNED TO APPLY MECHANICAL SHOCKS TO BONE CELLS

Laurent Navarro, Jean-Charles Pinoli, Henri Besset, René Guyonnet, Laurence Vico, Alain Guignandon

Abstract

A new device called biomechanical stimulation device (BSD) has been recently developped and is under patenting process. This BSD allows to apply shocks to a biomaterial disc, on which bone cells have been seeded. To observe the real behaviour of the biomaterial under shock loading, the BSD is instrumented with an impact hammer and an accelerometer. Force and acceleration signals are recorded, and signal analysis can be performed, in particular Fourier analysis. The results obtained lead to a better understanding of the stimulus that the cells can perceive at the top surface of the biomaterial disc. It appears that mechanical shocks applied at 1 Hps (Hit per second) or 10 Hps generate a frequency content up to 35 kHz. The main further objective will be to characterize the influence of mechanical shocks on bone cells proliferation.

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Paper Citation


in Harvard Style

Navarro L., Pinoli J., Besset H., Guyonnet R., Vico L. and Guignandon A. (2008). A NEW INSTRUMENTED BIOLOGICAL DEVICE DESIGNED TO APPLY MECHANICAL SHOCKS TO BONE CELLS . In Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008) ISBN 978-989-8111- 17-3, pages 272-278. DOI: 10.5220/0001047002720278


in Bibtex Style

@conference{biodevices08,
author={Laurent Navarro and Jean-Charles Pinoli and Henri Besset and René Guyonnet and Laurence Vico and Alain Guignandon},
title={A NEW INSTRUMENTED BIOLOGICAL DEVICE DESIGNED TO APPLY MECHANICAL SHOCKS TO BONE CELLS},
booktitle={Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)},
year={2008},
pages={272-278},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001047002720278},
isbn={978-989-8111- 17-3},
}


in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)
TI - A NEW INSTRUMENTED BIOLOGICAL DEVICE DESIGNED TO APPLY MECHANICAL SHOCKS TO BONE CELLS
SN - 978-989-8111- 17-3
AU - Navarro L.
AU - Pinoli J.
AU - Besset H.
AU - Guyonnet R.
AU - Vico L.
AU - Guignandon A.
PY - 2008
SP - 272
EP - 278
DO - 10.5220/0001047002720278