SIMULTANEOUS WIRELESS MEASUREMENT OF BLOOD PRESSURE AND SYMPATHETIC NERVE ACTIVITY - A System for Investigating Neural Control Mechanisms in Long Term Blood Pressure Regulation

Daniel McCormick, Robert Kirton, Alan Easteal, Simon Malpas, Carolyn J. Barret, Sarah Jane Guild, Augio Patrick Hu, Poul Nielson, David Budgett, Matthew Lim, Bruce van Vliet

Abstract

We report on the development of a combined sympathetic nerve activity and blood pressure telemeter for long term implantation in freely moving small animals. The devices simultaneously records and transmits blood pressure, temperature and sympathetic nerve data on the 2.4 GHz ISM band with a range of 5 m. Blood pressure is measured with a 400 Hz bandwidth, fluid filled catheter at a resolution of 0.1 mmHg. Sympathetic nerve activity is measured differentially using stainless steel electrodes attached to the renal nerve. The telemeter measures 29x37x12mm (a volume of approximately 9.5 cm3) and weighs 17g, making it suitable for use in rats with a weight greater than 170 g. Battery life is 12 h when used continuously, however the device’s lifespan is effectively indefinite due to the use of in vivo inductively coupled battery charging. Example data recorded in a conscious unconstrained rat is provided which verifies the telemeters operation.

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Paper Citation


in Harvard Style

McCormick D., Kirton R., Easteal A., Malpas S., J. Barret C., Jane Guild S., Nielson P., Patrick Hu A., Budgett D., Lim M. and van Vliet B. (2008). SIMULTANEOUS WIRELESS MEASUREMENT OF BLOOD PRESSURE AND SYMPATHETIC NERVE ACTIVITY - A System for Investigating Neural Control Mechanisms in Long Term Blood Pressure Regulation . In Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008) ISBN 978-989-8111- 17-3, pages 204-209. DOI: 10.5220/0001050902040209


in Bibtex Style

@conference{biodevices08,
author={Daniel McCormick and Robert Kirton and Alan Easteal and Simon Malpas and Carolyn J. Barret and Sarah Jane Guild and Poul Nielson and Augio Patrick Hu and David Budgett and Matthew Lim and Bruce van Vliet},
title={SIMULTANEOUS WIRELESS MEASUREMENT OF BLOOD PRESSURE AND SYMPATHETIC NERVE ACTIVITY - A System for Investigating Neural Control Mechanisms in Long Term Blood Pressure Regulation},
booktitle={Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)},
year={2008},
pages={204-209},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001050902040209},
isbn={978-989-8111- 17-3},
}


in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)
TI - SIMULTANEOUS WIRELESS MEASUREMENT OF BLOOD PRESSURE AND SYMPATHETIC NERVE ACTIVITY - A System for Investigating Neural Control Mechanisms in Long Term Blood Pressure Regulation
SN - 978-989-8111- 17-3
AU - McCormick D.
AU - Kirton R.
AU - Easteal A.
AU - Malpas S.
AU - J. Barret C.
AU - Jane Guild S.
AU - Nielson P.
AU - Patrick Hu A.
AU - Budgett D.
AU - Lim M.
AU - van Vliet B.
PY - 2008
SP - 204
EP - 209
DO - 10.5220/0001050902040209