MICRO-SHAFT-POKING - A Novel Instrument for Mechanically Characterizing Soft Biomimetic Membrance

Kuo-Kang Liu, Mark Ahearne, Eleftherios Siamantouras, Ying Yang

Abstract

Characterizing viscoelastic properties of soft biomimetic membranes has become increasingly important due to their biomedical applications such as tissue engineering/regenerative medicine and biosensors. This paper presents a new micro-shaft-poking (MSP) technique which is free from the complication of substrate backing, normally occurred as an intractable problem in the conventional indentation testing for soft membranes. A tailored indention apparatus with a spherical indenter was constructed to achieve the force resolution and displacement of 1μN and 1μm. The biomimetic membranes which were used for mechanical testing were made of two types of hydrogel, alginate and agarose. The results showed that the elastic modulus increased with gel concentration. A creep test has also been conducted to examine the time-dependent behaviors of various hydrogel and a viscoelastic model has been correspondingly developed and applied to describe the experimental results. Other potential applications of this new instrument to other membranes, both artificial and biological, have been addressed in the paper.

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Paper Citation


in Harvard Style

Liu K., Ahearne M., Siamantouras E. and Yang Y. (2008). MICRO-SHAFT-POKING - A Novel Instrument for Mechanically Characterizing Soft Biomimetic Membrance . In Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008) ISBN 978-989-8111- 17-3, pages 210-215. DOI: 10.5220/0001051402100215


in Bibtex Style

@conference{biodevices08,
author={Kuo-Kang Liu and Mark Ahearne and Eleftherios Siamantouras and Ying Yang},
title={MICRO-SHAFT-POKING - A Novel Instrument for Mechanically Characterizing Soft Biomimetic Membrance},
booktitle={Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)},
year={2008},
pages={210-215},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001051402100215},
isbn={978-989-8111- 17-3},
}


in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)
TI - MICRO-SHAFT-POKING - A Novel Instrument for Mechanically Characterizing Soft Biomimetic Membrance
SN - 978-989-8111- 17-3
AU - Liu K.
AU - Ahearne M.
AU - Siamantouras E.
AU - Yang Y.
PY - 2008
SP - 210
EP - 215
DO - 10.5220/0001051402100215