POLYMER MEMS SYSTEM FOR MEASURING THE MECHANICAL MODULUS OF A BIOLOGICAL CELL

Wenyue Zhang, Markus Gnerlich, Yaohua Sun, Gaoshan Jing, Jonathan J. Paly, Arkady Voloshin, Svetlana Tatic-Lucic

Abstract

The measurements of the mechanical modulus of biological cells are critical to studies of pathophysiology and the research for an effective treatment. This research has developed a rapid and cost effective technique in order to measure the Poisson’s ratio and mechanical modulus of a live biological cell by utilizing microelectromechanical system (MEMS) techniques in a biological application. The design, fabrication, and characterization of a polymer-based MEMS system that integrates a V-shaped electrothermal actuator array and a cell-positioning system in a single microelectronics chip are presented here. This BioMEMS device compressed a NIH3T3 fibroblasts cell and caused up to 25% mechanical strain.

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Paper Citation


in Harvard Style

Zhang W., Gnerlich M., Sun Y., Jing G., J. Paly J., Voloshin A. and Tatic-Lucic S. (2008). POLYMER MEMS SYSTEM FOR MEASURING THE MECHANICAL MODULUS OF A BIOLOGICAL CELL . In Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008) ISBN 978-989-8111- 17-3, pages 146-150. DOI: 10.5220/0001052201460150


in Bibtex Style

@conference{biodevices08,
author={Wenyue Zhang and Markus Gnerlich and Yaohua Sun and Gaoshan Jing and Jonathan J. Paly and Arkady Voloshin and Svetlana Tatic-Lucic},
title={POLYMER MEMS SYSTEM FOR MEASURING THE MECHANICAL MODULUS OF A BIOLOGICAL CELL},
booktitle={Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)},
year={2008},
pages={146-150},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001052201460150},
isbn={978-989-8111- 17-3},
}


in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Biomedical Electronics and Devices - Volume 2: BIODEVICES, (BIOSTEC 2008)
TI - POLYMER MEMS SYSTEM FOR MEASURING THE MECHANICAL MODULUS OF A BIOLOGICAL CELL
SN - 978-989-8111- 17-3
AU - Zhang W.
AU - Gnerlich M.
AU - Sun Y.
AU - Jing G.
AU - J. Paly J.
AU - Voloshin A.
AU - Tatic-Lucic S.
PY - 2008
SP - 146
EP - 150
DO - 10.5220/0001052201460150