STUDY OF THE PROPERTIES OF BIOTIN-STREPTAVIDIN SENSITIVE BIOFETS

Thomas Windbacher, Viktor Sverdlov, Siegfried Selberherr, Clemens Heitzinger, Norbert Mauser, Christian Ringhofer

Abstract

In this work the properties of a biotin-streptavidin BioFET have been studied numerically with homogenized boundary interface conditions as the link between the oxide of the FET and the analyte which contains the biosample. The biotin-streptavidin reaction pair is used in purification and detection of various biomolecules; the strong streptavidin-biotin bond can also be used to attach biomolecules to one another or onto a solid support. Thus this reaction pair in combination with a FET as the transducer is a powerful setup enabling the detection of a wide variety of molecules with many advantages that stem from the FET, like no labeling, no need of expensive read-out devices, the possibility to put the signal amplification and analysis on the same chip, and outdoor usage without the necessity of a lab.

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Paper Citation


in Harvard Style

Windbacher T., Sverdlov V., Selberherr S., Heitzinger C., Mauser N. and Ringhofer C. (2009). STUDY OF THE PROPERTIES OF BIOTIN-STREPTAVIDIN SENSITIVE BIOFETS . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009) ISBN 978-989-8111- 64-7, pages 24-30. DOI: 10.5220/0001430700240030


in Bibtex Style

@conference{biodevices09,
author={Thomas Windbacher and Viktor Sverdlov and Siegfried Selberherr and Clemens Heitzinger and Norbert Mauser and Christian Ringhofer},
title={STUDY OF THE PROPERTIES OF BIOTIN-STREPTAVIDIN SENSITIVE BIOFETS},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009)},
year={2009},
pages={24-30},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001430700240030},
isbn={978-989-8111- 64-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009)
TI - STUDY OF THE PROPERTIES OF BIOTIN-STREPTAVIDIN SENSITIVE BIOFETS
SN - 978-989-8111- 64-7
AU - Windbacher T.
AU - Sverdlov V.
AU - Selberherr S.
AU - Heitzinger C.
AU - Mauser N.
AU - Ringhofer C.
PY - 2009
SP - 24
EP - 30
DO - 10.5220/0001430700240030