MINIATURIZED ELECTROCHEMICAL SENSING SYSTEMS FOR IN VITRO AND IN VIVO BIOMEDICAL APPLICATIONS

V. I. Ogurtsov, K. Twomey, N. V. Bakounine, C. Mc Caffrey, J. Doyle, V. Beni, D. W. M. Arrigan

Abstract

Development of miniaturized electrochemical sensing systems for in vitro and in vivo biomedical applications is discussed. The systems are based on high sensitivity potentiostatic instrumentation, which is suitable for chemical and biochemical sensors. The in vitro application is an 8 channel hand-held PC-controlled system with user-friendly interface. This is capable of implementing different electrochemical potentiodynamic techniques. The in vivo applications are realized using two approaches: a small sized PCB with commercially available ICs, and a specially developed on-chip system. The performance of the systems is validated through electrochemical characterization of a microarray sensor.

References

  1. Peng, Y., Hu, C., Zheng, D., & Hu, S. (2008). A sensitive nitric oxide microsensor based on PBPB composite film-modified carbon fiber microelectrode. Sensors and Actuators B-Chemical, in press.
  2. Seo, H., Park, D., Park, J. (2008). Fabrication and characterization of platinum black and mesoporous platinum electrodes for in-vivo and continuously monitoring electrochemical sensor applications. Thin Solid Films, 516(16), 5227-5230.
  3. Ndamanisha, J. C., & Guo, L. P. (2008). Electrochemical determination of uric acid at ordered mesoporous carbon functionalized with ferrocenecarboxylic acidmodified electrode. Biosensors & Bioelectronics, 23(11), 1680-1685.
  4. Wang, M., & Ha, Y. (2007). An electrochemical approach to monitor pH change in agar media during plant tissue culture. Biosensors & Bioelectronics, 22(11), 2718-2723.
  5. McLaughlin, G. W., Braden, K., Franc, B., & Kovacs, G. T. A. (2002). Microfabricated solid-state dissolved oxygen sensor. Sensors and Actuators B-Chemical, 83(1-3), 138-148.
  6. Abbaspour, A., & Mirzajani, R. (2007). Electrochemical monitoring of piroxicam in different pharmaceutical forms with multi-walled carbon nanotubes paste electrode. Journal of Pharmaceutical and Biomedical Analysis, 44(1), 41-48.
  7. Morales, M. D., Serra, B., de Prada, A. G. V., Reviejo, A. J., & Pingarron, J. M. (2007). An electrochemical method for simultaneous detection and identification of Escherichia coli, Staphylococcus aureus and Salmonella choleraesuis using a glucose oxidaseperoxidase composite biosensor. Analyst, 132(6), 572- 578.
  8. Shiddiky, M.J.A., Rahman, M.A., Choel, C.S., Shim, Y. (2008). Fabrication of disposable sensors for biomolecule detection using hydrazine electrocatalyst. Analytical Biochemistry, 379(2), 170-175.
Download


Paper Citation


in Harvard Style

I. Ogurtsov V., Twomey K., V. Bakounine N., Mc Caffrey C., Doyle J., Beni V. and W. M. Arrigan D. (2009). MINIATURIZED ELECTROCHEMICAL SENSING SYSTEMS FOR IN VITRO AND IN VIVO BIOMEDICAL APPLICATIONS . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009) ISBN 978-989-8111- 64-7, pages 83-87. DOI: 10.5220/0001546300830087


in Bibtex Style

@conference{biodevices09,
author={V. I. Ogurtsov and K. Twomey and N. V. Bakounine and C. Mc Caffrey and J. Doyle and V. Beni and D. W. M. Arrigan},
title={MINIATURIZED ELECTROCHEMICAL SENSING SYSTEMS FOR IN VITRO AND IN VIVO BIOMEDICAL APPLICATIONS},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009)},
year={2009},
pages={83-87},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001546300830087},
isbn={978-989-8111- 64-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009)
TI - MINIATURIZED ELECTROCHEMICAL SENSING SYSTEMS FOR IN VITRO AND IN VIVO BIOMEDICAL APPLICATIONS
SN - 978-989-8111- 64-7
AU - I. Ogurtsov V.
AU - Twomey K.
AU - V. Bakounine N.
AU - Mc Caffrey C.
AU - Doyle J.
AU - Beni V.
AU - W. M. Arrigan D.
PY - 2009
SP - 83
EP - 87
DO - 10.5220/0001546300830087