# MULTIVARIATE LINEAR REGRESSION BASED SYNTHESIS OF 12-LEAD ECG FROM THREE BIPOLAR LEADS

### Ivan Tomasic, Roman Trobec, Viktor Avbelj

#### Abstract

The development of new technologies for electrocardiographic (ECG) monitoring enables the optimization of ECG recording strategy, in terms of a number and a position of body electrodes. Emerging wireless technology, together with requirements for improved wearing comfort, dictates a special design of a wireless bipolar ECG lead, which is composed of two closely placed electrodes. The measurements from a set of wireless electrodes, can serve for the reconstruction of the standard 12-lead ECG, which is directly applicable for the current medical knowledge. We present a method for synthesizing 12-lead ECG from only three bipolar leads. The result of the proposed method, based on multivariate linear regression, is a coefficients vector that transforms the data from three bipolar leads to a synthesized 12-leads ECG with minimum loss of diagnostic information. Two presented test cases show that a linear combination of only three bipolar leads, each obtained from two electrodes on a distance of 5 cm, suffices for a reliable synthesis of a standard 12-lead ECG. Wireless ECG leads can constitute a body sensor network that eliminates the need for additional wires and therefore improves the applicability of ECG device technology.

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#### Paper Citation

#### in Harvard Style

Tomasic I., Trobec R. and Avbelj V. (2010). **MULTIVARIATE LINEAR REGRESSION BASED SYNTHESIS OF 12-LEAD ECG FROM THREE BIPOLAR LEADS** . In *Proceedings of the Third International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2010)* ISBN 978-989-674-016-0, pages 216-221. DOI: 10.5220/0002697702160221

#### in Bibtex Style

@conference{healthinf10,

author={Ivan Tomasic and Roman Trobec and Viktor Avbelj},

title={MULTIVARIATE LINEAR REGRESSION BASED SYNTHESIS OF 12-LEAD ECG FROM THREE BIPOLAR LEADS},

booktitle={Proceedings of the Third International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2010)},

year={2010},

pages={216-221},

publisher={SciTePress},

organization={INSTICC},

doi={10.5220/0002697702160221},

isbn={978-989-674-016-0},

}

#### in EndNote Style

TY - CONF

JO - Proceedings of the Third International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2010)

TI - MULTIVARIATE LINEAR REGRESSION BASED SYNTHESIS OF 12-LEAD ECG FROM THREE BIPOLAR LEADS

SN - 978-989-674-016-0

AU - Tomasic I.

AU - Trobec R.

AU - Avbelj V.

PY - 2010

SP - 216

EP - 221

DO - 10.5220/0002697702160221