AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS

M. Denaï, M. Mahfouf, A. Wang, D. A. Linkens, G. H. Mills

Abstract

Thoracic Electrical Impedance Tomography (EIT) is a non-invasive technique which attempts to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting small alternating currents via an electrode array placed on the surface of the thorax. Because air is highly resistive to electric currents whereas fluids and blood are good conductors, it is possible to detect changes in lungs air content with EIT enabling the assessment of ventilation distribution. This paper presents a physiological model which integrates a previously developed gas exchange model with a model of the lung mechanics. This model is combined with a two-dimensional (2D) finite element mesh of the thorax to simulate EIT image reconstruction in patients with acute Respiratory Distress Syndrome (ARDS) under mechanical ventilation. The model was able to track lung ventilation distribution under various simulated ARDS conditions and ventilator settings.

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Paper Citation


in Harvard Style

Denaï M., Mahfouf M., Wang A., A. Linkens D. and H. Mills G. (2010). AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS . In Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010) ISBN 978-989-674-018-4, pages 208-213. DOI: 10.5220/0002709502080213


in Bibtex Style

@conference{biosignals10,
author={M. Denaï and M. Mahfouf and A. Wang and D. A. Linkens and G. H. Mills},
title={AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS},
booktitle={Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010)},
year={2010},
pages={208-213},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002709502080213},
isbn={978-989-674-018-4},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010)
TI - AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS
SN - 978-989-674-018-4
AU - Denaï M.
AU - Mahfouf M.
AU - Wang A.
AU - A. Linkens D.
AU - H. Mills G.
PY - 2010
SP - 208
EP - 213
DO - 10.5220/0002709502080213