ADVANCED COMPUTER MODELING FOR INTERSTITIAL MICROWAVE HYPERTHERMIA THERAPY - Comparison of Two Numerical Methods in Computational Electromagnetics

M. F. J. Cepeda, A. Vera, L. Leija, E. Ávila-Navarro, C. Reig, E.A. Navarro

Abstract

Microwave hyperthermia therapy is a recent development in the field of tumor ablation. Eelectromagnetic microwave irradiation applied to the tumor tissue causes water molecules to vibrate and rotate, resulting in tissue heating and subsequently cell death via thermal-induced protein denaturation. To effectively treat deep-stead tumors, the interstitial antennas should produce a highly localized specific absorption rate pattern and be efficient radiators at different generator frequencies. Numerical electromagnetic and thermal simulations are used to optimize the antenna design and predict heating patterns. An advanced computer modeling of a double slot antenna for interstitial hyperthermia was designed using two different numerical methods, the Finite Element Method and a Finite-difference time-domain. The aim of this work is to compare and analyze both numerical methods.

References

  1. K. Ito, K. Saito, T. Taniguchi, H. Yoshimura, 2002. Temperature distribution in and around array applicator for interstitial microwave hyperthermia combined with interstitial radiation therapy," Proc. 27th Intl. URSI Gen. Assembly, Maastricht.
  2. Yee KS., 1966. Numerical solution of initial boundary value problems involving Maxwell's equations in isotropic media. IEEE Trans Ant Prop, AP-14:302- 307.
  3. Sullivan D., 1990. Three-dimensional computer simulation in deep regional hyperthermia using the finite-difference timedomain method. IEEE Trans Microw Theory Tech., 38:204-211.
  4. Haemmerich D, Chachati L, Wright AS, Mahvi DM, Lee FT, Webster JG., 2003. Hepatic radiofrequency ablation with internally cooled probes: Effect of coolant temperature on lesion size. IEEE Trans Biomed Eng., 50:493-500.
  5. John M Bertram, Deshan Yang, Mark C Converse, John G Webster and David M Mahvi, 2006. Antenna design for microwave hepatic ablation using an axisymmetric electromagnetic model BioMedical Engineering OnLine. Biomed Eng Online 5: 15.
  6. Wissler EH. Pennes'. 1948. Paper revisited. J Appl Physiol 1998;85(1):35-41.
  7. E. Ávila-Navarro, J.M. Blanes, J.A. Carrasco, C. Reig, E.A. Navarro, 2006. A new bi-faced log-periodic printed antenna, Microwave and Optical Technology Letters, vol. 48, No. 2, pp. 402-405.
  8. Cepeda M: F: J, Vera A and Leija L., Microcoaxial Double Slot Antenna for Insterstitial Hyperthermia: Modeling and Validation”, International Conference on Advances in Electronics and Micro-Electronics ENICS 2008, Valencia, Spain, September, 2008, 138- 143pp. ISBN: 978-0-7695-3370-4
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Paper Citation


in Harvard Style

Cepeda M., Vera A., Leija L., Ávila-Navarro E., Reig C. and Navarro E. (2010). ADVANCED COMPUTER MODELING FOR INTERSTITIAL MICROWAVE HYPERTHERMIA THERAPY - Comparison of Two Numerical Methods in Computational Electromagnetics . In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 166-169. DOI: 10.5220/0002711501660169


in Bibtex Style

@conference{biodevices10,
author={M. F. J. Cepeda and A. Vera and L. Leija and E. Ávila-Navarro and C. Reig and E.A. Navarro},
title={ADVANCED COMPUTER MODELING FOR INTERSTITIAL MICROWAVE HYPERTHERMIA THERAPY - Comparison of Two Numerical Methods in Computational Electromagnetics},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={166-169},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002711501660169},
isbn={978-989-674-017-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - ADVANCED COMPUTER MODELING FOR INTERSTITIAL MICROWAVE HYPERTHERMIA THERAPY - Comparison of Two Numerical Methods in Computational Electromagnetics
SN - 978-989-674-017-7
AU - Cepeda M.
AU - Vera A.
AU - Leija L.
AU - Ávila-Navarro E.
AU - Reig C.
AU - Navarro E.
PY - 2010
SP - 166
EP - 169
DO - 10.5220/0002711501660169