COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL

Alberto Olmo, Alberto Yúfera

Abstract

Electrical models for microelectrode-cell interfaces are essential to match electrical simulations to real bio-systems performance and correctly to decode the results obtained experimentally. The accurate response simulation of a microelectrode sensor to changes in the cell-electrode system, such as cell growth, enables the optimum microelectrode design process. We report the use of COMSOL quasi-static mode, contrary to other DC modes frequently used, including magnetic fields to calculate the bioimpedance of the system. A fully electrode-cell model has been built, and the effect of fibroblasts of different diameters on the simulated impedance of small microelectrodes (32-µm square) has been studied, in order to validate the model and to characterize the microelectrode sensor response to changes in cell size and density.

References

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Paper Citation


in Harvard Style

Olmo A. and Yúfera A. (2010). COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL . In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 178-182. DOI: 10.5220/0002740301780182


in Bibtex Style

@conference{biodevices10,
author={Alberto Olmo and Alberto Yúfera},
title={COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={178-182},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002740301780182},
isbn={978-989-674-017-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL
SN - 978-989-674-017-7
AU - Olmo A.
AU - Yúfera A.
PY - 2010
SP - 178
EP - 182
DO - 10.5220/0002740301780182