AN ASSESSMENT PROCEDURE INVOLVINGWAVEFORM SHAPES FOR PUPIL LIGHT REFLEX

Minoru Nakayama, Wioletta Nowak, Hitoshi Ishikawa, Ken Asakawa

Abstract

The waveforms of Pupillary Light Reflex (PLR) can be analyzed in a diagnostic test that allows for differentiation between disorders affecting photoreceptors and those affecting retinal ganglion cells. This position paper proposes quantitative comparison metrics for waveform shapes using Discrete Fourier Transform (DFT) descriptors (FDs), and another procedure for emphasizing stimuli and subject differences using MultiDimensional Scaling (MDS) and clustering, where dissimilarities between stimuli are defined using descriptors as waveform features. To determine the efficiency of the procedures, a set of PLR data from a conventional experiment for the determination of a melanopsin-associated photoreceptive system was analyzed. Though the captured data was based on single trial for the stimuli, and the number of samples was small, both characteristics of stimuli and subjects were quantitatively extracted using the proposed procedures. Therefore, the possibility of applying the procedures to clinical diagnostics using PLR was examined.

References

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Paper Citation


in Harvard Style

Nakayama M., Nowak W., Ishikawa H. and Asakawa K. (2010). AN ASSESSMENT PROCEDURE INVOLVINGWAVEFORM SHAPES FOR PUPIL LIGHT REFLEX . In Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010) ISBN 978-989-674-018-4, pages 322-326. DOI: 10.5220/0002756603220326


in Bibtex Style

@conference{biosignals10,
author={Minoru Nakayama and Wioletta Nowak and Hitoshi Ishikawa and Ken Asakawa},
title={AN ASSESSMENT PROCEDURE INVOLVINGWAVEFORM SHAPES FOR PUPIL LIGHT REFLEX},
booktitle={Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010)},
year={2010},
pages={322-326},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002756603220326},
isbn={978-989-674-018-4},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010)
TI - AN ASSESSMENT PROCEDURE INVOLVINGWAVEFORM SHAPES FOR PUPIL LIGHT REFLEX
SN - 978-989-674-018-4
AU - Nakayama M.
AU - Nowak W.
AU - Ishikawa H.
AU - Asakawa K.
PY - 2010
SP - 322
EP - 326
DO - 10.5220/0002756603220326