RAPID PROTOTYPING OF 3D ANATOMICAL MODELS TO HEMODYNAMIC STUDIES

Vania Freitas, Luis Queijo, Rui Lima

Abstract

The purpose of this work is mainly to manufacture several anatomical models in a polymeric material – polydimensiloxane (PDMS) to study the blood flow through a carotid artery bifurcation. Over the last few decades, research has been shown that the geometry of the carotid artery is closely related to the development of serious cardiovascular diseases. Hence, there is a considerable interest in the development of in vitro experimental techniques able to obtain accurate measurements of the blood flow behavior through a realistic carotid artery. In this study we decide to apply rapid prototyping (RP) technologies combined with a PDMS casting technique in order to fabricate an anatomically realistic model of a human carotid to investigate, in a near future, the effect of the geometry on the local hemodynamics and consequently improve the understanding of the origin and development of these pathologies. Based on a human carotid computerized tomography (TC) it has been developed a 3D model through the application of two rapid prototyping techniques – Fused Deposition Modeling (FDM) and Tridimensional Printing (TDP). By combining the rapid prototyping techniques with a PDMS casting technique it was possible at the end to obtain an anatomically transparent model of a human carotid artery made by an elastomeric material, i.e. PDMS. Hence, we believe that this combination is a promising technique to perform in vitro blood studies through anatomically realistic models, such as a carotid artery.

References

  1. Alves, Fernando; et al., 2001. Prototipagem Rápida. Protoclick, Porto.
  2. Collins, Tucker, Robbins, Stanley L., Cotran, Ramzi S., Kumar, Vinay, 2001. Fundamentos de Robbins - Patologia Estrutural e Funcional, Guanabara Koogan. Brasil, Sexta edição.
  3. Foggiatto, J. A., 2006. O Uso da Prototipagem Rápida na Área Médico-Odontológica. Tecnologia & Humanismo, 60-68.
  4. Goldsmith, H., Turitto, V., 1986. Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report-Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis. Thromb Haemost. 55(3), 415-435
  5. Lima, R.. et al., 2007. In vitro confocal micro-PIV measurements of blood flow in a square microchannel: the effect of the haematocrit on instantaneous velocity profiles. Journal of Biomechanics, 40, 2752-2757
  6. Lima, R., et al., 2008. In vitro blood flow in a rectangular PDMS microchannel: experimental observations using a confocal micro-PIV system. Biomedical Microdevices, 10(2),153-67
  7. Queijo, Luís, Rocha, João, Barreira, Luísa, Pereira, Paulo Miguel, Barbosa, Tiago, San Juan, Manuel, 2009. A surgical training model manufacture using rapid prototyping technology. Innovative developments in design and manufacturing - Advanced Research in Virtual and Rapid Prototyping, Taylor & Francis.
  8. Rocha, J. & Alves, L., 2000. Utilização de moldações cerâmicas compósitas no fabrico de ferramentas metálicas. 2º Encontro nacional do colégio de engenharia mecânica da ordem dos engenheiros. Coimbra. Portugal.
  9. Williams, P.L, Warwick, R., 1995. Gray's Anatomy, Churchill Livingstone. Edinburgh, 38th Edition.
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Paper Citation


in Harvard Style

Freitas V., Queijo L. and Lima R. (2010). RAPID PROTOTYPING OF 3D ANATOMICAL MODELS TO HEMODYNAMIC STUDIES . In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: Special Session RAPID-Bio, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 246-251. DOI: 10.5220/0002787702460251


in Bibtex Style

@conference{special session rapid-bio10,
author={Vania Freitas and Luis Queijo and Rui Lima},
title={RAPID PROTOTYPING OF 3D ANATOMICAL MODELS TO HEMODYNAMIC STUDIES},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: Special Session RAPID-Bio, (BIOSTEC 2010)},
year={2010},
pages={246-251},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002787702460251},
isbn={978-989-674-017-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: Special Session RAPID-Bio, (BIOSTEC 2010)
TI - RAPID PROTOTYPING OF 3D ANATOMICAL MODELS TO HEMODYNAMIC STUDIES
SN - 978-989-674-017-7
AU - Freitas V.
AU - Queijo L.
AU - Lima R.
PY - 2010
SP - 246
EP - 251
DO - 10.5220/0002787702460251