APPROACH TO ENABLE AN AUTOMATIC PRE-PROCESSING OF qRT-PCR - Analysis

Marco Franke, Klaus-Dieter Thoben, Rainer Söller

Abstract

A fully automated analysis method for real-time PCR samples can be achieved through an automated noise removal. This results in a guaranteed robustness against the factors that repeatedly impact the analysis of real-time PCR data and usually lead to a manual analysis by skilled experts. The presented approach attains a degree of robustness which allows an automated analysis for real-time PCR. This new automated pre-processing method improves the real-time PCR data for the analysis in such a way that accepted qualitative analysis methods can be used in an automated way. Furthermore, the article shows an evaluation of an implemented demonstrator for an automated analysis which combines the developed pre-processing method with the second derivation method for the qualitative analysis.

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Paper Citation


in Harvard Style

Franke M., Thoben K. and Söller R. (2012). APPROACH TO ENABLE AN AUTOMATIC PRE-PROCESSING OF qRT-PCR - Analysis . In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012) ISBN 978-989-8425-90-4, pages 281-285. DOI: 10.5220/0003734102810285


in Bibtex Style

@conference{bioinformatics12,
author={Marco Franke and Klaus-Dieter Thoben and Rainer Söller},
title={APPROACH TO ENABLE AN AUTOMATIC PRE-PROCESSING OF qRT-PCR - Analysis},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012)},
year={2012},
pages={281-285},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003734102810285},
isbn={978-989-8425-90-4},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012)
TI - APPROACH TO ENABLE AN AUTOMATIC PRE-PROCESSING OF qRT-PCR - Analysis
SN - 978-989-8425-90-4
AU - Franke M.
AU - Thoben K.
AU - Söller R.
PY - 2012
SP - 281
EP - 285
DO - 10.5220/0003734102810285