Managing Data and Knowledge for the InmunoFlu Research Project

G. Lopez Campos, Enrique de Andres, R. Almansa, I. Martin-Loeches, V. Lopez-Alonso, J. F. Bermejo-Martin, F. Martin-Sanchez


The InmunoFlu project was funded during 2009-2011 by the Government of Spain (Biomedical Research Fund-FIS) for the study of the H1N1pdm influenza. It was an integrative project were clinicians from intensive care units (ICUs) across Spain came together with fundamental researchers to analyse at the molecular level the H1N1 infection. The multidisciplinary and geographical dispersion of the participants required the development of data and knowledge management tools. The InmunoFlu database was developed as a tool for the storage of all clinical data from patients associated with the ICUs and for the subsequent clinical annotation of the samples used in the molecular analysis of the infection and host response. The dispersion of participants in different centres fostered the development of InmunoFlu Web portal, a collaborative web portal using web 2.0 technologies, which served as a knowledge management tool for the project community. The web portal enabled among other characteristics document sharing as well as other collaborative tools such as chat, wiki, etc... The use of both tools played a central role in the success of this complex project.


  1. Taubenberger J. K., Reid A. H., Janczewski T. A., Fanning T. G., 2001. Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virus. Philos Trans R Soc Lond B Biol Sci. 29;356(1416):1829-39
  2. Cheng V. C., To K. K., Tse H., Hung I. F., Yuen K. Y., 2012. Two years after pandemic influenza A/2009/H1N1: what have we learned?. Clin Microbiol Rev. 25(2):223-63.
  3. Kersun L. S., Coffin S. E., Leckerman K. H., Ingram M., Reilly A. F., 2010. Community Acquired Influenza requiring Hospitalization:Vaccine Status Is Unrelated to Morbidity in Children With Cancer. Pediatr Blood Cancer. 54(1):79-82.
  4. Bertolini G., Rossi C., Crespi D., Finazzi S., Morandotti M., Rossi S., Peta M., Langer M., Poole D., 2011. Is influenza A(H1N1) pneumonia more severe than other community-acquired pneumonias? Results of the GiViTI survey of 155 Italian ICUs Intensive Care Med. 37(11):1746-55. Epub 2011 Aug 17
  5. Chen H., 2001. Knowledge management systems: A text mining perspective. The university of Arizona.
  6. Montani S., Bellazzi R., 2002. Supporting decisions in medical applications: the knowledge management perspective. Int J Med Inform. 18;68(1-3):79-90
  7. Steels L., Corporate knowledge management, 1993. Proceedings of ISMICK 7893, Compiegne, France, pp. 9-30.
  8. De Andres Galiana E., Lopez-Alonso V., Salamanca Rodriguez L., Hermosilla Gimeno I., Martin-Sanchez F., 2009. BIKMAS 2.0: A BIomedical Knowledge Management Antenna System. Proceedings Medcine 2.0. 2009 Toronto.

Paper Citation

in Harvard Style

Lopez Campos G., de Andres E., Almansa R., Martin-Loeches I., Lopez-Alonso V., Bermejo-Martin J. and Martin-Sanchez F. (2013). Managing Data and Knowledge for the InmunoFlu Research Project . In Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2013) ISBN 978-989-8565-37-2, pages 181-186. DOI: 10.5220/0004227701810186

in Bibtex Style

author={G. Lopez Campos and Enrique de Andres and R. Almansa and I. Martin-Loeches and V. Lopez-Alonso and J. F. Bermejo-Martin and F. Martin-Sanchez},
title={Managing Data and Knowledge for the InmunoFlu Research Project},
booktitle={Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2013)},

in EndNote Style

JO - Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2013)
TI - Managing Data and Knowledge for the InmunoFlu Research Project
SN - 978-989-8565-37-2
AU - Lopez Campos G.
AU - de Andres E.
AU - Almansa R.
AU - Martin-Loeches I.
AU - Lopez-Alonso V.
AU - Bermejo-Martin J.
AU - Martin-Sanchez F.
PY - 2013
SP - 181
EP - 186
DO - 10.5220/0004227701810186