Improving Neuron Stimulation Efficency by Altering Electrode Geometry

A. Ghazavi, D. Westwick, C. Luk, N. I. Syed, C. Dalton


Microelectrode arrays (MEA) are non-invasive tools for recording brain cell activity and have been successfully applied to a variety of neurons. However, MEAs fail where consistent stimulation of neurons is desired over an extended period of time. Here, a model is presented to study features that provide optimum stimulation threshold from different sizes and shapes of electrodes. Both simulation and in vitro experimental results suggest that star-shaped electrodes enable a threshold voltage that is 25% lower than that of an electrode with a circular shape, and are thus considered more efficient for neuronal stimulation. These findings are important as they will help produce more efficient microelectrode arrays for in vivo applications such as prosthetic devices, as well as for long-term in vitro neuron stimulation for studying neuronal networks and function.


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Paper Citation

in Harvard Style

Ghazavi A., Westwick D., Luk C., Syed N. and Dalton C. (2013). Improving Neuron Stimulation Efficency by Altering Electrode Geometry . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2013) ISBN 978-989-8565-34-1, pages 51-56. DOI: 10.5220/0004238900510056

in Bibtex Style

author={A. Ghazavi and D. Westwick and C. Luk and N. I. Syed and C. Dalton},
title={Improving Neuron Stimulation Efficency by Altering Electrode Geometry},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2013)},

in EndNote Style

JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2013)
TI - Improving Neuron Stimulation Efficency by Altering Electrode Geometry
SN - 978-989-8565-34-1
AU - Ghazavi A.
AU - Westwick D.
AU - Luk C.
AU - Syed N.
AU - Dalton C.
PY - 2013
SP - 51
EP - 56
DO - 10.5220/0004238900510056