Quantitative Scoring of Muscle Involvement in MRI of Neuromuscular Diseases

Maria Evelina Fantacci, Guja Astrea, Roberta Battini, Alessandra Retico, Chiara Sottocornola, Michela Tosetti

Abstract

An automated method to evaluate the fat infiltration in tissues has been developed and applied to images of the human leg. The final aim is to obtain a quantitative evaluation of fat infiltration percentage and to relate it to the grade of muscle impairment in subjects affected by Neuro-Muscular Diseases (NMD). Through a muscle segmentation algorithm on structural T1-weighted magnetic resonance images (MRIs), the estimated non-muscle percentage (eNMP) in the segmented muscle area has been evaluated in healthy subjects as a reference value. A semi-automated procedure allows extending the algorithm to MRIs of NMD patients. A strong correlation has been demonstrated between the eNMP index and the disease severity.

References

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Paper Citation


in Harvard Style

Fantacci M., Astrea G., Battini R., Retico A., Sottocornola C. and Tosetti M. (2015). Quantitative Scoring of Muscle Involvement in MRI of Neuromuscular Diseases . In Proceedings of the International Conference on Bioimaging - Volume 1: BIOIMAGING, (BIOSTEC 2015) ISBN 978-989-758-072-7, pages 100-105. DOI: 10.5220/0005255801000105


in Bibtex Style

@conference{bioimaging15,
author={Maria Evelina Fantacci and Guja Astrea and Roberta Battini and Alessandra Retico and Chiara Sottocornola and Michela Tosetti},
title={Quantitative Scoring of Muscle Involvement in MRI of Neuromuscular Diseases},
booktitle={Proceedings of the International Conference on Bioimaging - Volume 1: BIOIMAGING, (BIOSTEC 2015)},
year={2015},
pages={100-105},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005255801000105},
isbn={978-989-758-072-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bioimaging - Volume 1: BIOIMAGING, (BIOSTEC 2015)
TI - Quantitative Scoring of Muscle Involvement in MRI of Neuromuscular Diseases
SN - 978-989-758-072-7
AU - Fantacci M.
AU - Astrea G.
AU - Battini R.
AU - Retico A.
AU - Sottocornola C.
AU - Tosetti M.
PY - 2015
SP - 100
EP - 105
DO - 10.5220/0005255801000105