The Theta/Beta Ratio as an Indicator of Evolution in Pediatric Patients Treated for Attention-Deficit/Hyperactivity Disorder (ADHD) - A Retrospective Study

María Evangelina Herrán-Paz, Raúl Ortiz-Monasterio, Antonio Rodríguez-Díaz, Olivia Mendoza, Juan R. Castro, Hector J. Willys

Abstract

This study was performed to assess whether the theta/beta ratio can be regarded as an indicator of pediatric patients’ evolution while receiving treatment for ADHD. This required a spectral analysis of the electrophysiological power output from several channels with reference at the vertex (Cz). The files and EEG signals of sixteen clinical cases, which included children and adolescents from 4 to 16 years of age, were analyzed. The analysis of the EEG signals was performed using the Fast Fourier Transform (FFT) to obtain the frequency bands. Patients were under pharmacological treatment for at least one year and had at least 2 EEG studies. The results indicate that a good correlation exists between the theta/beta ratio and the patient’s clinical evolution. 42% of the patients who had 3 or more EEG’s, showed good correlation (r > 0.9), which was coherent with their good clinical evolution. 33% showed linear tendency (0.63 < r < 0.73), with variable response and recovery tendency. 25% had bad correlation (r < 0.3), also with variable treatment response. These results relate to poor adherence to the pharmacological treatment.

References

  1. Adler, L. D., & Nierenberg, A. A. (2010). Review of medication adherence in children and adults with ADHD. Postgraduate Medicine, 122(1), 184-191.
  2. Becker, S., Langberg, J., Vaughn, A., & Epstein, J. (2012). Clinical Utility of the Vanderbilt ADHD Diagnostic Parent Rating Scale Comorbidity Screening Scales. Journal of Developmental & Behavioral Pediatrics, 33(3), 221-228.
  3. Fogelman, Y., & Kahan, E. (2007). Common Dilemmas in the Diagnosis and Treatment of ADHD. Experts' Opinions for the Improvement of Practice Management in the Outpatient Setting. Archivos En Medicina Familiar, 9(1), 41-48.
  4. Graham, J., Banaschewski, T., Buitelaar, J., Coghill, D., Danckaerts, M., Dittmann, R. W., … Taylor, E. (2011). European guidelines on managing adverse effects of medication for ADHD. European Child & Adolescent Psychiatry, 20(1), 17-37. doi:10.1007/s00787-010-0140-6
  5. Herrán Paz, M. E., Ortiz Monasterio, R., Herrán Ramírez, M. A., Rodríguez-Díaz, A., & García Villalpando, A. K. (2014). Narrative review of scales assessing attention-deficit/hyperactivity disorder in children and adolescents. Medwave, 14(01), e5887-e5887. doi:10.5867/medwave.2014.01.5887
  6. Monastra, V. J. (2008). Quantitative electroencephalography and attentiondeficit/hyperactivity disorder: implications for clinical practice. Current Psychiatry Reports, 10(5), 432-8. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/18803918
  7. Polanczyk, G., Lima, M., & Horta, B. (2007). The worldwise prevalence of ADHD: a systematic review and meta-regression analysis. American Journal of Psychiatry, 164(6), 942-948.
  8. Quintana, H., Snyder, S. M., Purnell, W., Aponte, C., & Sita, J. (2007). Comparison of a standard psychiatric evaluation to rating scales and EEG in the differential diagnosis of attention-deficit/hyperactivity disorder. Psychiatry Research, 152(2-3), 211-222.
  9. Ruiz, G. M., & Sauceda, G. J. M. (2012). Trastorno por déficit de atención a lo largo de la vida. México: Alfil.
  10. Snyder, S. M., & Hall, J. R. (2006). A meta-analysis of quantitative EEG power associated with attentiondeficit hyperactivity disorder. Journal of Clinical Neurophysiology, 23(5), 440-55. doi:10.1097/01.wnp.0000221363.12503.78
  11. Snyder, S. M., Quintana, H., Sexson, S. B., Knott, P., Haque, A. F. M., & Reynolds, D. A. (2008). Blinded, multi-center validation of EEG and rating scales in indentifying ADHD within a clinical sample. Psychiatry Research, 159, 346-358. Retrieved from www.sciencedirect.com
  12. Vaquerizo-Madrid, J. (2008). Evaluación clínica del trastorno por déficit de atención/hiperactividad, modelo de entrevista y controversias. REV NEUROL, 46(1), S37-S41.
  13. Wolraich, M., Bard, D., Neas, B., Doffing, M., & Beck, L. (2012). The Psychometric Properties of the Vanderbilt Attention-Deficit Hyperactivity Disorder Diagnostic Teacher Rating Scale in a Community Population. Journal of Developmental & Behavioral Pediatrics, 34(2), 83-93.
  14. Wolraich, M., Lambert, W., & Doffing, M. et al. (2003). Psychometric properties of the Vanderbilt ADHD diagnostic parent rating scale in a referred population. Journal of Pediatric Psychology, 28(8), 559-568. doi:10.1093/jpepsy/jsg046
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Paper Citation


in Harvard Style

Evangelina Herrán-Paz M., Ortiz-Monasterio R., Rodríguez-Díaz A., Mendoza O., R. Castro J. and J. Willys H. (2015). The Theta/Beta Ratio as an Indicator of Evolution in Pediatric Patients Treated for Attention-Deficit/Hyperactivity Disorder (ADHD) - A Retrospective Study . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015) ISBN 978-989-758-069-7, pages 277-282. DOI: 10.5220/0005268502770282


in Bibtex Style

@conference{biosignals15,
author={María Evangelina Herrán-Paz and Raúl Ortiz-Monasterio and Antonio Rodríguez-Díaz and Olivia Mendoza and Juan R. Castro and Hector J. Willys},
title={The Theta/Beta Ratio as an Indicator of Evolution in Pediatric Patients Treated for Attention-Deficit/Hyperactivity Disorder (ADHD) - A Retrospective Study},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015)},
year={2015},
pages={277-282},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005268502770282},
isbn={978-989-758-069-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015)
TI - The Theta/Beta Ratio as an Indicator of Evolution in Pediatric Patients Treated for Attention-Deficit/Hyperactivity Disorder (ADHD) - A Retrospective Study
SN - 978-989-758-069-7
AU - Evangelina Herrán-Paz M.
AU - Ortiz-Monasterio R.
AU - Rodríguez-Díaz A.
AU - Mendoza O.
AU - R. Castro J.
AU - J. Willys H.
PY - 2015
SP - 277
EP - 282
DO - 10.5220/0005268502770282