A Smart Catheter System for Minimally Invasive Brain Monitoring

Dongxuan Bao, Zhuo Zou, Yuxiang Huan, Chuanying Zhai, Tiberiu Bagaian, Hannu Tenhunen, Bengt Källbäck, Li-Rong Zheng

Abstract

This paper demonstrates a smart catheter system with intracranial pressure (ICP) and temperature sensing capability which is designed for real-time monitoring in traumatic brain injury (TBI) therapy. It uses a single flexible catheter with a 1 mm (3 Fr) diameter that integrates electrodes and sophisticated silicon chip on flexible substrates, enabling multimodality monitoring of physiological signals. A micro-electro-mechanical-system (MEMS) catheter pressure sensor is mounted on the distal end. It can be used for detecting both pressure and temperature by different switch configurations, which minimizes the size of catheter and reduces the cost. The interconnects (signalling conductors) are printed on a bio-compatible flexible substrate, and the sensor is interfaced with an embedded electronic system at the far-end. The electronic system consists of analog front end with analog-to-digital converter (ADC), a microcontroller, and data interface to the hospital infrastructure with a graphical user interface (GUI). The overall smart catheter system achieves a pressure sensing root mean square error (RMSE) of +-1.5 mmHg measured from 20 mmHg to 300 mmHg above 1 atm and a temperature sensing RMSE of +-0.08 ºC measured from 32 ºC to 42 ºC. The sampling rate can be up to 10S/s. The in vivo performance is demonstrated in laboratory animals.

References

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Paper Citation


in Harvard Style

Bao D., Zou Z., Huan Y., Zhai C., Bagaian T., Tenhunen H., Källbäck B. and Zheng L. (2015). A Smart Catheter System for Minimally Invasive Brain Monitoring . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2015) ISBN 978-989-758-071-0, pages 198-203. DOI: 10.5220/0005285501980203


in Bibtex Style

@conference{biodevices15,
author={Dongxuan Bao and Zhuo Zou and Yuxiang Huan and Chuanying Zhai and Tiberiu Bagaian and Hannu Tenhunen and Bengt Källbäck and Li-Rong Zheng},
title={A Smart Catheter System for Minimally Invasive Brain Monitoring},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2015)},
year={2015},
pages={198-203},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005285501980203},
isbn={978-989-758-071-0},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2015)
TI - A Smart Catheter System for Minimally Invasive Brain Monitoring
SN - 978-989-758-071-0
AU - Bao D.
AU - Zou Z.
AU - Huan Y.
AU - Zhai C.
AU - Bagaian T.
AU - Tenhunen H.
AU - Källbäck B.
AU - Zheng L.
PY - 2015
SP - 198
EP - 203
DO - 10.5220/0005285501980203