Encoding of Movement in Local Field Potentials from the Wall of Motor Cortical Lesions in Rats

Ioana Nica, Marjolijn Deprez, Frederik Ceyssens, Kris van Kuyck, Robert Puers, Bart Nuttin, Jean-Marie Aerts

Abstract

Cortical lesions can severely impact normal motor function and a better understanding of the neural electrical activity at the level of the lesion can help optimize current rehabilitation techniques. Here, we study local field potentials (LFPs) recorded from within the cavity wall of cortical lesions, induced in the forelimb area of the rat motor cortex. We report prominent theta and gamma oscillatory activity, on data collected from three rats. We show that these oscillations are strongly linked to movement intervals, in an open-field experimental setup that required neither learning nor reward. These results should be extended into a further investigation to test the hypothesis that LFPs can help parametrize the animal's state of impairment.

References

  1. Buzsaki, G., Anastassiou, C.A., Koch, C., 2012. The origin of extracellular fields and currents - EEG, ECoG, LFP and spikes. Nat. Rev. Neurosci. 13(6):407-420. doi: 10.1038/nrn3241.
  2. Ceyssens, F., van Kuyck, K., Velde, G. V., Welkenhuysen, M., Stappers, L., Nuttin, B., Puers, R.,. 2013. Resorbable scaffold based chronic neural electrode arrays. Biomedical microdevices, 15(3): 481- 493.
  3. Igarashi J., et al., 2013. A ?-? oscillation code for neuronal coordination during motor behaviour. J. Neurosci. 33:18515-18530.
  4. Miller, K. J., Sorensen, L. B., Ojemann, J. G. & den Nijs, M. 2009. Power-law scaling in the brain surface electric potential. PLoS Comput. Biol. 5, e1000609.
  5. Von Nicolai, C., et al., 2014. Corticostriatal Coordination through Coherent Phase-Amplitude Coupling. J. Neurosci. 34(17):5938-5948.
Download


Paper Citation


in Harvard Style

Nica I., Deprez M., Ceyssens F., van Kuyck K., Puers R., Nuttin B. and Aerts J. (2015). Encoding of Movement in Local Field Potentials from the Wall of Motor Cortical Lesions in Rats . In - NEUROTECHNIX, ISBN , pages 0-0


in Bibtex Style

@conference{neurotechnix15,
author={Ioana Nica and Marjolijn Deprez and Frederik Ceyssens and Kris van Kuyck and Robert Puers and Bart Nuttin and Jean-Marie Aerts},
title={Encoding of Movement in Local Field Potentials from the Wall of Motor Cortical Lesions in Rats},
booktitle={ - NEUROTECHNIX,},
year={2015},
pages={},
publisher={SciTePress},
organization={INSTICC},
doi={},
isbn={},
}


in EndNote Style

TY - CONF
JO - - NEUROTECHNIX,
TI - Encoding of Movement in Local Field Potentials from the Wall of Motor Cortical Lesions in Rats
SN -
AU - Nica I.
AU - Deprez M.
AU - Ceyssens F.
AU - van Kuyck K.
AU - Puers R.
AU - Nuttin B.
AU - Aerts J.
PY - 2015
SP - 0
EP - 0
DO -