Hyperbaric Oxygen (HBO) Heals Cell Through Reactive Oxygen Species (ROS)

Handi Suyono, Guritno Suryokusumo

Abstract

Abstract: In degenerative diseases, hypoxia is the fundamental mechanism. Hypoxia stimulate reactive oxygen species (ROS) production. ROS interact with protein, lipid, DNA, and other cell’s components and cause damage. Hyperbaric oxygen (HBO) improves clinical outcomes but the exact mechanism is still debated. HBO reverses hypoxia state. HBO increases ROS production because of hyperoxia but it can heal the cell. HBO-induced ROS stimulates endogenous antioxidants, hypoxia-inducible factors, and heat shock proteins. HBO-induced ROS theoretically improves telomere length and telomerase activity. Superoxide is converted into hydrogen peroxide and it acts as signal transduction. ROS has positive outcomes in maintaining cell survival.

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Paper Citation


in Harvard Style

Suyono H. and Suryokusumo G. (2017). Hyperbaric Oxygen (HBO) Heals Cell Through Reactive Oxygen Species (ROS).In Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS, ISBN 978-989-758-340-7, pages 123-127. DOI: 10.5220/0007334001230127


in Bibtex Style

@conference{sips17,
author={Handi Suyono and Guritno Suryokusumo},
title={Hyperbaric Oxygen (HBO) Heals Cell Through Reactive Oxygen Species (ROS)},
booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},
year={2017},
pages={123-127},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007334001230127},
isbn={978-989-758-340-7},
}


in EndNote Style

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,
TI - Hyperbaric Oxygen (HBO) Heals Cell Through Reactive Oxygen Species (ROS)
SN - 978-989-758-340-7
AU - Suyono H.
AU - Suryokusumo G.
PY - 2017
SP - 123
EP - 127
DO - 10.5220/0007334001230127