Effects of Moderate Intensity Aerobic Exercise on MMP-9 Level, NOx Plasma Level and Resting Blood Pressure in Sedentary Elderly Women With Overweight

Suhartini SM, Gusbakti R, Ilyas EII

Abstract

Abstract: Background: Aging is a dominant risk factor for most forms of cardiovascular disease. Sedentary lifestyle in elderly with obesity can decrease the function of cardiovascular system. Previous study determined that moderate intensity aerobic exercise was highly recommended in elderly because the type of exercise can improve body fitness and oxidative damage due to aging. Objective: The aims of this study was to investigate the effect of moderate intensity aerobic exercise on Matrix Metalloproteinase-9 (MMP-9) level, NOx plasma level, systolic blood pressure (SBP) and diastolic blood pressure (DBP) in sedentary elderly women with overweight. Metode : The research method is quasi experimental with pre test and post test design. The sample included 33 volunteer sedentary elderly women overweight with age 65,11±4,85 years old that divided on two group that is the experimental group (EG/ n=17) and control group (CG/ n=16). EG performed moderate intensity aerobic exercise (walking) during 30 min per session, intensity 50–80% heart rate maximum, three times per week for 12 week. The examination of MMP-9 and NOx plasma level by ELISA method and resting blood pressure by auscultation method. Data was processed by unpaired t-test. Results : Experimental group had significantly lower level of MMP-9 (-38,188 p 0,024) and SBP (-10,294 p 0,001) than CG. NOx plasma level showed significantly decreases in both group (p < 0,05), but the decreasing trend was found to be higher in the CG. DBP and body mass index (BMI) did not change (p >0,05). Conclusions: The results suggest a role MMP-9 level in the vascular adaptation during exercise in elderly women and moderate intensity aerobic exercise can delay the reduction of NO due to aging proceses.

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Paper Citation


in Harvard Style

SM S., R G. and EII I. (2017). Effects of Moderate Intensity Aerobic Exercise on MMP-9 Level, NOx Plasma Level and Resting Blood Pressure in Sedentary Elderly Women With Overweight.In Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS, ISBN 978-989-758-340-7, pages 265-270. DOI: 10.5220/0007337302650270


in Bibtex Style

@conference{sips17,
author={Suhartini SM and Gusbakti R and Ilyas EII},
title={Effects of Moderate Intensity Aerobic Exercise on MMP-9 Level, NOx Plasma Level and Resting Blood Pressure in Sedentary Elderly Women With Overweight},
booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},
year={2017},
pages={265-270},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007337302650270},
isbn={978-989-758-340-7},
}


in EndNote Style

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,
TI - Effects of Moderate Intensity Aerobic Exercise on MMP-9 Level, NOx Plasma Level and Resting Blood Pressure in Sedentary Elderly Women With Overweight
SN - 978-989-758-340-7
AU - SM S.
AU - R G.
AU - EII I.
PY - 2017
SP - 265
EP - 270
DO - 10.5220/0007337302650270