Pathophysiology of Irritable Bowel Syndrome

Rastita Widyasari, Iswan Abbas Nusi, Poernomo Boedi Setiawan, Herry Purbayu, Titong Sugihartono, Ummi Maimunah, Ulfa Kholili, Budi Widodo, Husin Thamrin, Amie Vidyani, Muhammad Miftahussurur


Irritable bowel syndrome (IBS) is a large bowel functional disorder characterized by abdominal pain or discomfort and is associated with bowel habit changes without organic disorder. IBS is affected by many factors and is suspected of involving central and peripheral mechanisms, such as gastrointestinal dysmotility, bowel visceral/mucosal hypersensitivity, increased bowel permeability and interaction among the luminal factors including food and bowel microbiota changes, bowel epithelial barrier, mucosa immunity, genetic factor and biopsychosocial and brain gut axis which are suspected to affect IBS pathophysiology. Understanding the various factors and mechanisms underlying IBS helps in the consideration of management and repair of patients’ prognosis


Paper Citation

in Harvard Style

Widyasari R., Nusi I., Setiawan P., Purbayu H., Sugihartono T., Maimunah U., Kholili U., Widodo B., Thamrin H., Vidyani A. and Miftahussurur M. (2017). Pathophysiology of Irritable Bowel Syndrome.In Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS, ISBN 978-989-758-340-7, pages 470-476. DOI: 10.5220/0007340704700476

in Bibtex Style

author={Rastita Widyasari and Iswan Abbas Nusi and Poernomo Boedi Setiawan and Herry Purbayu and Titong Sugihartono and Ummi Maimunah and Ulfa Kholili and Budi Widodo and Husin Thamrin and Amie Vidyani and Muhammad Miftahussurur},
title={Pathophysiology of Irritable Bowel Syndrome},
booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},

in EndNote Style


JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,
TI - Pathophysiology of Irritable Bowel Syndrome
SN - 978-989-758-340-7
AU - Widyasari R.
AU - Nusi I.
AU - Setiawan P.
AU - Purbayu H.
AU - Sugihartono T.
AU - Maimunah U.
AU - Kholili U.
AU - Widodo B.
AU - Thamrin H.
AU - Vidyani A.
AU - Miftahussurur M.
PY - 2017
SP - 470
EP - 476
DO - 10.5220/0007340704700476