# Abnormal Uterine Bleeding with Three Different Doses and Intervals of Hormonal Contraceptive Injection

### Ananda Febina Kimresti A, Ashon Sa'adi, Lilik Djuari, Maftuhah Rochmanti

#### Abstract

This study aimed to prove the effectiveness and compare the side-effects of abnormal uterine bleeding in three contraceptive injection groups based on the amount of bleeding, the duration of bleeding and menstruation regularity. The three groups were group A with 65 mg of MPA and 7.5 mg of E2C given every two months, group B with 120 mg of MPA and 10 mg of E2C given every three months and group C with 25 mg of MPA and 5 mg of E2C given every month as the positive control. The data were analyzed using Chi-square and Mann-Whitney tests. Chi-square test results showed that between groups A and C, the p value of bleeding amount was 0.935 (p > 0.05), between groups A and B was 0.000 (p < 0.05, odds ratio: 6.103) and between groups A and C was 0.000 (p < 0.05, odds ratio: 6.33). The p value of menstruation period between groups A and C was 0.057 (p > 0.05), between groups A and B was 0.488 (p > 0.05, odds ratio: 2.300) and between groups B and C was 0.000 (p < 0.05, odds ratio: 1.02). The p value of menstruation regularity in the three groups was 0.000. The three medication groups had the same effectiveness as contraception despite the difference of abnormal uterine bleeding in each group

Download#### Paper Citation

#### in Harvard Style

Kimresti A A., Sa'adi A., Djuari L. and Rochmanti M. (2017). **Abnormal Uterine Bleeding with Three Different Doses and Intervals of Hormonal Contraceptive Injection**.In *Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,* ISBN 978-989-758-340-7, pages 491-496. DOI: 10.5220/0007341104910496

#### in Bibtex Style

@conference{sips17,

author={Ananda Febina Kimresti A and Ashon Sa'adi and Lilik Djuari and Maftuhah Rochmanti},

title={Abnormal Uterine Bleeding with Three Different Doses and Intervals of Hormonal Contraceptive Injection},

booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},

year={2017},

pages={491-496},

publisher={SciTePress},

organization={INSTICC},

doi={10.5220/0007341104910496},

isbn={978-989-758-340-7},

}

#### in EndNote Style

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,

TI - Abnormal Uterine Bleeding with Three Different Doses and Intervals of Hormonal Contraceptive Injection

SN - 978-989-758-340-7

AU - Kimresti A A.

AU - Sa'adi A.

AU - Djuari L.

AU - Rochmanti M.

PY - 2017

SP - 491

EP - 496

DO - 10.5220/0007341104910496