Index Predictive of Drug Resistant Tuberculosis (MDR-TB) on Tuberculosis Patients

Ariska Putri Hidayathillah, Chatarina Umbul W, Hari Basuki N

Abstract

The resistance of the M. Tuberculosis germ to anti-tuberculosis drugs is a state in which germs can no longer be killed by first-line medicine, such as isoniazid and rifampicin. Indonesia is in 8th place out of 27 countries that have a high burden of MDR-TB. Gresik district is not among the top 10 districts in East Java, which have the highest TB incidence, but Gresik was a district with the highest proportion of MDR-TB cases among TB cases in East Java in 2015. The research design of this study is case control. The sampling technique is simple random sampling. Based on the analysis using multiple logistic regression, the index of incidence of MDR-TB obtained as Drugs Swallowing Control p= 0.002, regularity p= 0.000, side effects of drugs p= 0.001, the result of previous treatment p= 0.000 and DM p= 0.001. This prediction index can predict the risk of MDR-TB occurring in Gresik with 90.2% sensitivity and 78.9% specificity with measurement accuracy is 84.1%. It can be concluded that the index of incidence of MDR-TB is 4.359 + 2.137 (Drugs Swallowing Control) + 2.885 (regularity) + 2.094 (drug side effects) + 1.926 (previous treatment) + 2.013 (diabetes mellitus).

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Paper Citation


in Harvard Style

Hidayathillah A., W C. and N H. (2017). Index Predictive of Drug Resistant Tuberculosis (MDR-TB) on Tuberculosis Patients.In Proceedings of the 2nd International Symposium of Public Health - Volume 1: ISOPH, ISBN 978-989-758-338-4, pages 227-231. DOI: 10.5220/0007511902270231


in Bibtex Style

@conference{isoph17,
author={Ariska Putri Hidayathillah and Chatarina Umbul W and Hari Basuki N},
title={Index Predictive of Drug Resistant Tuberculosis (MDR-TB) on Tuberculosis Patients},
booktitle={Proceedings of the 2nd International Symposium of Public Health - Volume 1: ISOPH,},
year={2017},
pages={227-231},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007511902270231},
isbn={978-989-758-338-4},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Symposium of Public Health - Volume 1: ISOPH,
TI - Index Predictive of Drug Resistant Tuberculosis (MDR-TB) on Tuberculosis Patients
SN - 978-989-758-338-4
AU - Hidayathillah A.
AU - W C.
AU - N H.
PY - 2017
SP - 227
EP - 231
DO - 10.5220/0007511902270231