Correlation between Parasite Density with TNF-α and IL-10 in Plasmodium Falciparum Infected Patients in East Sumba District, East Nusa Tenggara Province

Akhmad Mubarok, Heny Arwati, Yoes Prijatna Dahlan

Abstract

Introduction: Malaria is caused by female mosquito anopheles bite transmitting malaria parasite sporozoite stage into the human body. Data Word Health Organization shows case causing malaria death to reach 429.000, this need commitment of every country to overcome malaria. Indonesia is still a malaria endemic area and includes a country with a high risk of malaria. Population migration from malaria endemic areas to non-endemic areas of malaria is responsible for malaria transmission, especially in Papua, West Papua, Maluku, North Maluku and East Nusa Tenggara. Malaria case in East Nusa Tenggara Province 7,05% per 1000 population based on annual parasite icidence (API) and 36,039 positive. East Sumba 12,84% per 1000 population. Methods: A descriptive cross sectional study was conducted in East Sumba district using the Logical Framework approach. Twenty two people were involved in this study with ranging age 4 to 50 years. The presence of density parasit be examined using microscope, cytokine TNF-α and Interleukin-10 analyzed using enzyme linked immunosorbent assay (ELISA) Result: Significant values considered at p<0,05. The result show that parasite density 7.72 ± 9.51 /μl. TNF-α 27.14 ± 50.22 pg/ml IL-10 2.20 ± 3.23 pg/ml Conclusion: The result from this study conclude parasite density increases of TNF-α and IL-10 cytokine.

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in Harvard Style

Mubarok A., Arwati H. and Dahlan Y. (2018). Correlation between Parasite Density with TNF-α and IL-10 in Plasmodium Falciparum Infected Patients in East Sumba District, East Nusa Tenggara Province.In Proceedings of the 2nd International Conference Postgraduate School - Volume 1: ICPS, ISBN 978-989-758-348-3, pages 412-417. DOI: 10.5220/0007544004120417


in Bibtex Style

@conference{icps18,
author={Akhmad Mubarok and Heny Arwati and Yoes Prijatna Dahlan},
title={Correlation between Parasite Density with TNF-α and IL-10 in Plasmodium Falciparum Infected Patients in East Sumba District, East Nusa Tenggara Province},
booktitle={Proceedings of the 2nd International Conference Postgraduate School - Volume 1: ICPS,},
year={2018},
pages={412-417},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007544004120417},
isbn={978-989-758-348-3},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference Postgraduate School - Volume 1: ICPS,
TI - Correlation between Parasite Density with TNF-α and IL-10 in Plasmodium Falciparum Infected Patients in East Sumba District, East Nusa Tenggara Province
SN - 978-989-758-348-3
AU - Mubarok A.
AU - Arwati H.
AU - Dahlan Y.
PY - 2018
SP - 412
EP - 417
DO - 10.5220/0007544004120417