The Relationship between Body Composition and Physical Activity in Patients with Crohn’s Disease

Maurizio Marra, Olivia Di Vincenzo, Iolanda Cioffi, Rosa Sammarco, Luca Scalfi, Fabrizio Pasanisi


Crohn’s disease (CD) is a chronic inflammatory gastrointestinal disease associated with malnutrition, inadequate intake, increased energy expenditure, impaired digestion and absorption, leading to a reduction in skeletal muscle mass and adipose tissue. The purpose of this study was to evaluate body composition, phase angle (PhA) and muscular strength in a group of patients with CD. Forty-six male patients, participated in the study and were divided into two groups: 10 physically active patients (A-, age 29.1±8.9 years; weight 68.5±7.2 kg; height 172±4 cm; BMI 23.2±2.7 kg/m2) and 36 sedentary (S-, age 28.9±7.4 years; weight 67.7±8.6 kg; height 174±6 cm; BMI 22.4±2.5 kg/m2). Additionally, 20 healthy control subjects (CONTR, age 30.8±9.2 years; weight 71.4±5.6 kg; height 176±5 cm; BMI 23.1±2.1 kg/m2) participated in the study. S- presented significantly lower FFM values compared to control subjects (p<0.05) but not than A-; whereas no differences were observed for fat mass values between groups. Whole-body PhA was higher in A- than other groups; while upper-limbs PhA was lower in S than other groups and lower-limbs PhA was higher in A- than S- but not compared to controls. Finally, muscular strength resulted statistically lower in S- than C- but not than A-.


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