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Authors: Filippo Castiglione 1 and Francesco Pappalardo 2

Affiliations: 1 National Research Council of Italy, Italy ; 2 University of Catania, Italy

Keyword(s): Mathematical Biology, Computational Methods, Multi-Scale Models, Systems Biology.

Abstract: One of the most formidable challenges in modern biology is to get a unified view of the various mechanisms governing the behavior and of the causal relationships among different parts of a living system. It is coming clearer nowadays that to get such comprehensive picture computational models embracing different observation levels in space and time have to be formulated to explain the enormous amount of data deriving from -omic high throughput measurements methods. In this article we aim at giving a meaning to the concept of multi-scale modeling in the framework of studies of biological systems with particular interest in understanding human physiology in disease conditions.

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Paper citation in several formats:
Castiglione, F. and Pappalardo, F. (2013). Computational Biology Modeling across Different Scales. In Proceedings of the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2013) - BIOMED; ISBN 978-989-8565-69-3; ISSN 2184-2841, SciTePress, pages 617-625. DOI: 10.5220/0004405706170625

@conference{biomed13,
author={Filippo Castiglione. and Francesco Pappalardo.},
title={Computational Biology Modeling across Different Scales},
booktitle={Proceedings of the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2013) - BIOMED},
year={2013},
pages={617-625},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004405706170625},
isbn={978-989-8565-69-3},
issn={2184-2841},
}

TY - CONF

JO - Proceedings of the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2013) - BIOMED
TI - Computational Biology Modeling across Different Scales
SN - 978-989-8565-69-3
IS - 2184-2841
AU - Castiglione, F.
AU - Pappalardo, F.
PY - 2013
SP - 617
EP - 625
DO - 10.5220/0004405706170625
PB - SciTePress