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Authors: Marissa Astari 1 ; Afif Nurul Hidayati 2 ; Medhi Denisa Alinda 2 ; Bagus Haryo Kusumaputra 2 ; Linda Astari 2 ; M. Yulianto Listiawan 1 ; Indropo Agusni 2 ; Fedik A. Rantam 3 ; 4 ; Sunarso Suyoso 1 ; Evy Ervianti 1 ; Linda Astari 5 ; Yuri Widia 2 ; Sylvia Anggraeni 2 and Cita Rosita Sigit Prakoeswa 1

Affiliations: 1 Department of Dermatology Venereology, Faculty of Medicine, Universitas Airlangga, Dr Soetomo General Hospital,Surabaya, Indonesia ; 2 Department of Dermatology Venereology, Faculty of Medicine Universitas Airlangga, Dr Soetomo General Hospital,Surabaya, Indonesia ; 3 Stem Cell Research and Development Center, Universitas Airlangga, Surabaya, Indonesia. ; 4 Virology and Immunology Laboratory, Department of Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia ; 5 Departement of Dermatology and Venereology, Dr. Soetomo Teaching Hospital / School of Medicine, Universitas Airlangga, Surabaya, Indonesia

Keyword(s): human amniotic membrane stem cells, vitamin E, chronic plantar ulcer, leprosy

Abstract: Leprosy ulcers are mostly present in plantar pedis especially in areas with bony prominance. Plantar ulcers healimg in leprosy ide often dificult and time comsuming because of the declining of growth factors and cytokines as a result of a prolonged inflammatory condition. A 70-years old man working as pedicab driver had an ulcer at his left feet since 2 yaers ago, painless and not itchy. On regio caput metatarsal digiti 1 pedis sinistra there were 4 x 4 x 0,4 cm with necrotic tissue around. The patient was suffering from borderline leprosy since 10 years and already finished the treatment without history of drop out. We applied topical human amniotic membrane mesenchymal stem cells-conditioned medium (hAMMSC-CM) combine with vitamin E gel for 5 weeks and the ulcer healed completely.

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Paper citation in several formats:
Astari, M.; Hidayati, A.; Alinda, M.; Kusumaputra, B.; Astari, L.; Listiawan, M.; Agusni, I.; Rantam, F.; Suyoso, S.; Ervianti, E.; Astari, L.; Widia, Y.; Anggraeni, S. and Prakoeswa, C. (2021). A Case Report: Role of Human Amniotic Membrane Mesenchymal Stem Cells-Conditioned Medium (hAMMSC-CM) Combine with Vitamin E for Treating Chronic Plantar Pedis Ulcer in Leprosy Patient. In Proceedings of the 23rd Regional Conference of Dermatology - RCD; ISBN 978-989-758-494-7, SciTePress, pages 493-495. DOI: 10.5220/0008160504930495

@conference{rcd21,
author={Marissa Astari. and Afif Nurul Hidayati. and Medhi Denisa Alinda. and Bagus Haryo Kusumaputra. and Linda Astari. and M. Yulianto Listiawan. and Indropo Agusni. and Fedik A. Rantam. and Sunarso Suyoso. and Evy Ervianti. and Linda Astari. and Yuri Widia. and Sylvia Anggraeni. and Cita Rosita Sigit Prakoeswa.},
title={A Case Report: Role of Human Amniotic Membrane Mesenchymal Stem Cells-Conditioned Medium (hAMMSC-CM) Combine with Vitamin E for Treating Chronic Plantar Pedis Ulcer in Leprosy Patient},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - RCD},
year={2021},
pages={493-495},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008160504930495},
isbn={978-989-758-494-7},
}

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - RCD
TI - A Case Report: Role of Human Amniotic Membrane Mesenchymal Stem Cells-Conditioned Medium (hAMMSC-CM) Combine with Vitamin E for Treating Chronic Plantar Pedis Ulcer in Leprosy Patient
SN - 978-989-758-494-7
AU - Astari, M.
AU - Hidayati, A.
AU - Alinda, M.
AU - Kusumaputra, B.
AU - Astari, L.
AU - Listiawan, M.
AU - Agusni, I.
AU - Rantam, F.
AU - Suyoso, S.
AU - Ervianti, E.
AU - Astari, L.
AU - Widia, Y.
AU - Anggraeni, S.
AU - Prakoeswa, C.
PY - 2021
SP - 493
EP - 495
DO - 10.5220/0008160504930495
PB - SciTePress

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