Author:
Shula Shazman
Affiliation:
Department of Mathematics and Computer Science, The Open University, Derech Hauniversita 1, Raanana, Israel
Keyword(s):
Machine Learning, Decision Tree, Type 2 Diabetes, Insulin Resistance, Precision Medicine, Intermittent Fasting, Alternate Day Fasting.
Abstract:
Intermittent fasting (IF) is the cycling between periods of eating and fasting. The main types of IF are: complete alternate-day fasting; time-restricted feeding (eating within specific time frames such as the most prevalent 16:8 fast, with 16 hours of fasting and 8 hours for eating); religious fasting such as the Ramadan (occurs one month per year, with eating taking place only after nightfall). IF can be effective in reducing metabolic disorders and age-related diseases by bringing about changes in metabolic parameters associated with type 2 diabetes. Questions do remain, however, about the effects of the different types of IF as a function of the age at which fasting begins, gender and severity of type 2 diabetes. In this paper we describe a machine learning approach to selecting the best type of IF to improve health in type 2 diabetes. For the purposes of this research, the health outcomes of interest are changes in fasting glucose and insulin. The different types of intermittent
fast offer promising non-pharmacological approaches to improving health at the population level, with multiple public health benefits.
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