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Authors: Rila Suryani 1 ; Nazaruddin Nazaruddin 2 ; Kartini Hasballah 3 ; Muhammad Diah 3 ; Hardi Yusuf 4 ;  Juniarti 5 ; Syaifullah Muhammad 6 and  Khairan 7

Affiliations: 1 Magister Program, Department of Chemistry, Universitas Syiah Kuala, Banda Aceh, Indonesia ; 2 Department of Chemistry, Universitas Syiah Kuala, Banda Aceh, Indonesia ; 3 Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia ; 4 Department of Chemistry, Universitas Tadulako, Palu, Sulawesi Tengah, Indonesia ; 5 Herbal Research Centre, Universitas Yarsi, Jakarta, Indonesia ; 6 PUI-Nilam Aceh-Atsiri Research Centre, Universitas Syiah Kuala, Banda Aceh, Indonesia ; 7 PUI-Nilam Aceh-Atsiri Research Centre, Universitas Syiah Kuala, Banda Aceh, Departement of Pharmacy, Universitas Syiah Kuala, Banda Aceh, Pusat Riset Obat Herbal, Universitas Syiah Kuala, Banda Aceh, Pusat Riset Etnoscience, Universitas Syiah Kuala, Banda Aceh, Indonesia

Keyword(s): Conjugation Reaction, Citronellal, L-tyrosine, Staphylococcus aureus, Escherichia coli, Candida albicans

Abstract: The study of citronellal with L-tyrosin conjugation for antimicrobial properties has been conducted. The aim of this study to determine the relationship stucture between two compounds citronellal and L-tyrosine on antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans. The conjugation product obtained was yellow-white solid amorphous with the Rf value was 0.84 and the percentage of yield was 71.12%. The FT-IR spectra peak at 3205.69 cm-1 is represented the N-H stretching vibration from L-tyrosine, while the spectra appears at 1460.11 - 1438.90 cm-1 are represented the C=N which derived from imine or immonium from shift base reaction between citronellal and L-tyrosine. The GC-MS analysis showed that the peak 15 observed at RT 10.27 min. be expected a conjugation product with the m/z 316 [M+H]+ ion. The antimicrobial activity were determined by well diffusion method and the results showed that product of conjugation were have no antimicrobail activ ities at concentration tested (More)

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Paper citation in several formats:
Suryani, R.; Nazaruddin, N.; Hasballah, K.; Diah, M.; Yusuf, H.; Juniarti.; Muhammad, S. and Khairan. (2020). Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi. In Proceedings of the 2nd International Conference of Essential Oils - ICEO; ISBN 978-989-758-456-5, SciTePress, pages 74-79. DOI: 10.5220/0009957000740079

@conference{iceo20,
author={Rila Suryani. and Nazaruddin Nazaruddin. and Kartini Hasballah. and Muhammad Diah. and Hardi Yusuf. and Juniarti. and Syaifullah Muhammad. and Khairan.},
title={Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi},
booktitle={Proceedings of the 2nd International Conference of Essential Oils - ICEO},
year={2020},
pages={74-79},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009957000740079},
isbn={978-989-758-456-5},
}

TY - CONF

JO - Proceedings of the 2nd International Conference of Essential Oils - ICEO
TI - Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi
SN - 978-989-758-456-5
AU - Suryani, R.
AU - Nazaruddin, N.
AU - Hasballah, K.
AU - Diah, M.
AU - Yusuf, H.
AU - Juniarti.
AU - Muhammad, S.
AU - Khairan.
PY - 2020
SP - 74
EP - 79
DO - 10.5220/0009957000740079
PB - SciTePress

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