Independent Component Analysis and Raman Microspectroscopy on Paraffinised Non Dewaxed Cutaneous Biopsies: A promising Methodology for Melanoma Early Diagnosis

Cyril Gobinet, Ali Tfayli, Olivier Piot, Valeriu Vrabie, Régis Huez

2005

Abstract

This paper deals with a promising methodology for melanoma early diagnosis. Raman spectroscopy is used to record vibrational information of paraffinised tumoral tissues. Independent Component Analysis (ICA) is performed on Raman spectra to numerically deparaffinise spectra. Resulting deparaffinised spectra are used to extract discriminant information specific to malignant and benign tumors. These spectral specificities can be employed as molecular descriptors of the type of pathology. A comparison with Principal Component Analysis (PCA) shows that ICA is more suited to process this kind of problem.

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Paper Citation


in Harvard Style

Gobinet C., Tfayli A., Piot O., Vrabie V. and Huez R. (2005). Independent Component Analysis and Raman Microspectroscopy on Paraffinised Non Dewaxed Cutaneous Biopsies: A promising Methodology for Melanoma Early Diagnosis . In Proceedings of the 1st International Workshop on Biosignal Processing and Classification - Volume 1: BPC, (ICINCO 2005) ISBN 972-8865-35-X, pages 19-26. DOI: 10.5220/0001195500190026


in Bibtex Style

@conference{bpc05,
author={Cyril Gobinet and Ali Tfayli and Olivier Piot and Valeriu Vrabie and Régis Huez},
title={Independent Component Analysis and Raman Microspectroscopy on Paraffinised Non Dewaxed Cutaneous Biopsies: A promising Methodology for Melanoma Early Diagnosis},
booktitle={Proceedings of the 1st International Workshop on Biosignal Processing and Classification - Volume 1: BPC, (ICINCO 2005)},
year={2005},
pages={19-26},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001195500190026},
isbn={972-8865-35-X},
}


in EndNote Style

TY - CONF
JO - Proceedings of the 1st International Workshop on Biosignal Processing and Classification - Volume 1: BPC, (ICINCO 2005)
TI - Independent Component Analysis and Raman Microspectroscopy on Paraffinised Non Dewaxed Cutaneous Biopsies: A promising Methodology for Melanoma Early Diagnosis
SN - 972-8865-35-X
AU - Gobinet C.
AU - Tfayli A.
AU - Piot O.
AU - Vrabie V.
AU - Huez R.
PY - 2005
SP - 19
EP - 26
DO - 10.5220/0001195500190026