RELATIONSHIP BETWEEN QUANTITATIVE T-WAVE ALTERNANS ESTIMATES AND PARAMETERS DESCRIBING CLINICAL STATUS OF PATIENT IN ACCUTE PHASE OF MYOCARDIAL INFARCTION AND OUTCOME RESULTS

Algimantas Krisciukaitis, Renata Simoliuniene, Andrius Macas, Robertas Petrolis, Eimante Kamile Puodziunaite, Zita Bertasiene, Viktoras Saferis

2012

Abstract

Relationship between parameters describing clinical status of the patient in acute phase of myocardial infarction, outcome results and quantitative estimates of T-wave alternans, known prognostic factor of severe cardiac arrhythmias or sudden cardiac death, was investigated in aim to reveal their usefulness and incremental diagnostic utility. Integrated estimate, reflecting differences between S-T,T complexes of odd and even cardiocycles, obtained by means of Principal Component Analysis showed significant correlation with Left Ventricular Ejection Fraction and rehospitalization of patient within 6 months.

References

  1. Bloomfield D. M., Steinman R. C., Namerow P. B., Parides M., Davidenko J., Kaufman E. S., Shinn T., Curtis A., Fontaine J., Holmes D., et al., Microvolt Twave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II conundrum. Circulation 2004;110:1885- 1889.
  2. Chan P. S., Kereiakes D. J., Bartone C., Chow T., Usefulness of microvolt T-wave alternans to predict outcomes in patients with ischemic cardiomyopathy beyond one year. Am J. Cardiol. 2008 Aug 1;102(3):280-4.
  3. Chan P. S., Nallamothu B. K., Chow T., Microvolt Twave alternans: where do we go from here? [letter to the editor]. J. Am Coll Cardiol 2006;47:1736.
  4. Chow T., Kereiakes D. J., Bartone C., Booth T., Schloss E. J., Waller T., Chung E., Menon S., Nallamothu B. K., Chan P. S., Prognostic utility of microvolt T-wave alternans in risk stratifying patients with ischemic cardiomyopathy. J. Am Coll Cardiol 2006;47:1820 - 1827.
  5. Clifford G. D., Nemati S., Sameni R., An Artificial MultiChannel Model for Generating Abnormal Electrocardiographic Rhythms. Computers in Cardiology 2008;35:773-776
  6. Dregunas K., Povilonis E., Cardiac output and hemodynamic monitoring system “Heartlab”. "Biomedical engineering" (Proc.Int.Conf.), Kaunas 1999, p.100-105.
  7. Gehi A. K., Stein R. H., Metz L. D., Gomes JA. Microvolt T-wave alternans for the risk stratification of ventricular tachyarrhythmic events: a meta-analysis. J. Am Coll Cardiol 2005;46:75- 82.
  8. Hering H. E., Experimentelle studien an Saugetieren uber das Elektrocardiogram. Zeitschrift für experimentelle Pathologie und Therapie 1909;7:363-378.
  9. Krisciukaitis A., Tamosiunas M., Jakuska P., Veteikis R., Lekas R., Saferis V., Benetis R., Evaluation of ischemic injury of the cardiac tissue by using the principal component analysis of an epicardial electrogram. Comput Methods Programs Biomed. 2006 May; 82(2):121-129.
  10. Martínez J. P. and Olmos S., Methodological Principles Of Twa Analysis: A Unified Framework. IEEE Transactions On Biomedical Engineering, Vol. 52, No. 4, April 2005.
  11. Moody G. B., The PhysioNet / Computers in Cardiology Challenge 2008: T-Wave Alternans. Computers in Cardiology 2008;35:505-508.
  12. Nearing B. D. and Verrier R. L., Modified moving average analysis of T-wave alternans to predict ventricular fibrillation with high accuracy. J. Appl Physiol 92: 41- 549, 2002;
  13. Nearing B. D., Verrier R. L., Tracking cardiac electrical instability by computing interlead heterogeneity of Twave morphology. J. Appl Physiol 2003;95:2265- 2272.
  14. Nieminen T., Verrier R. L., Usefulness of T-wave alternans in sudden death risk stratification and guiding medical therapy. Ann Noninvasive Electrocardiol. 2010 Jul;15(3):276-88.
  15. Simoliuniene R., Krisciukaitis A., Macas A., Baksyte G., Saferis V., Zaliunas R., Principal Component Analysis Based Method for Detection and Evaluation of ECG T-Wave Alternans. Computers in Cardiology 2008, vol. 1-2, p. 757-760.
  16. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Eur Heart J. 1996;17:354-81.
  17. Wold S, Cross-validatory estimation of the number of components in factor and pricipal component models. Technometrics, (1978) 20 pp. 397-405.
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Paper Citation


in Harvard Style

Krisciukaitis A., Simoliuniene R., Macas A., Petrolis R., Puodziunaite E., Bertasiene Z. and Saferis V. (2012). RELATIONSHIP BETWEEN QUANTITATIVE T-WAVE ALTERNANS ESTIMATES AND PARAMETERS DESCRIBING CLINICAL STATUS OF PATIENT IN ACCUTE PHASE OF MYOCARDIAL INFARCTION AND OUTCOME RESULTS . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012) ISBN 978-989-8425-89-8, pages 448-452. DOI: 10.5220/0003856404480452


in Bibtex Style

@conference{biosignals12,
author={Algimantas Krisciukaitis and Renata Simoliuniene and Andrius Macas and Robertas Petrolis and Eimante Kamile Puodziunaite and Zita Bertasiene and Viktoras Saferis},
title={RELATIONSHIP BETWEEN QUANTITATIVE T-WAVE ALTERNANS ESTIMATES AND PARAMETERS DESCRIBING CLINICAL STATUS OF PATIENT IN ACCUTE PHASE OF MYOCARDIAL INFARCTION AND OUTCOME RESULTS},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)},
year={2012},
pages={448-452},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003856404480452},
isbn={978-989-8425-89-8},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)
TI - RELATIONSHIP BETWEEN QUANTITATIVE T-WAVE ALTERNANS ESTIMATES AND PARAMETERS DESCRIBING CLINICAL STATUS OF PATIENT IN ACCUTE PHASE OF MYOCARDIAL INFARCTION AND OUTCOME RESULTS
SN - 978-989-8425-89-8
AU - Krisciukaitis A.
AU - Simoliuniene R.
AU - Macas A.
AU - Petrolis R.
AU - Puodziunaite E.
AU - Bertasiene Z.
AU - Saferis V.
PY - 2012
SP - 448
EP - 452
DO - 10.5220/0003856404480452