Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis

T. Pinheiro, C. Ramos, P. Napoleão, C. Mendonça, C. Fondinho, M. Selas, M. Mota Carmo, R. Cruz Ferreira

2013

Abstract

The relationship between plaque morphology and clinical presentation was examined. Lumen dimensions, atheroma morphology and composition were assessed by virtual histology intravascular ultrasound (VH-IVUS) in 1757 frames of coronary segments of interest of 17 patients with acute and chronic coronary artery disease, i.e., ST-elevation (STEMI) and non-ST-elevation (NSTEMI) myocardial infarction, unstable angina (UA) and stable angina (SA). Large plaque areas with distended elastic lamina (EEL), rich in fibrotic (FB) and fibro-fatty (FF) tissues associated with STEMI and UA. Variants of this phenotype consisting of large calcium deposits and reduced lumen area were prevalent in NSTEMI patients. SA patients consistently showed plaques with small areas, marked constrictive growth and low FF content. IVUS-derived plaque measures provided phenotypes of vulnerability and rupture that may help improving risk stratification of both symptomatic and asymptomatic patients.

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Paper Citation


in Harvard Style

Pinheiro T., Ramos C., Napoleão P., Mendonça C., Fondinho C., Selas M., Mota Carmo M. and Cruz Ferreira R. (2013). Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis . In Proceedings of the International Congress on Cardiovascular Technologies - Volume 1: VisualCardio, (CARDIOTECHNIX 2013) ISBN 978-989-8565-78-5, pages 84-89. DOI: 10.5220/0004664400840089


in Bibtex Style

@conference{visualcardio13,
author={T. Pinheiro and C. Ramos and P. Napoleão and C. Mendonça and C. Fondinho and M. Selas and M. Mota Carmo and R. Cruz Ferreira},
title={Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis},
booktitle={Proceedings of the International Congress on Cardiovascular Technologies - Volume 1: VisualCardio, (CARDIOTECHNIX 2013)},
year={2013},
pages={84-89},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004664400840089},
isbn={978-989-8565-78-5},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Congress on Cardiovascular Technologies - Volume 1: VisualCardio, (CARDIOTECHNIX 2013)
TI - Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis
SN - 978-989-8565-78-5
AU - Pinheiro T.
AU - Ramos C.
AU - Napoleão P.
AU - Mendonça C.
AU - Fondinho C.
AU - Selas M.
AU - Mota Carmo M.
AU - Cruz Ferreira R.
PY - 2013
SP - 84
EP - 89
DO - 10.5220/0004664400840089