Identification of Standard Parameter of Mindi Leaves (Melia
azedrach L.) based on Indonesian Herbal Pharmacopeia
for Anti-cancer Herbal
Sukardiman*, Devky Rivina, Lusiana Arifianti, Herra Studiawan
Department of Pharmacognosy and Phytochemistry,
Faculty of Pharmacy
Universitas Airlangga, Surabaya
Keywords : standard parameter, raw material, Melia azedarch L.
Abstract : Mindi (Melia azedarch L) has a potency to be developed as anti-anticaner agent. The raw material is
affected by many factors such as cultivation, post harvest and processing. Standard parameters were
used to ensure safety, efficacy and quality of the product. This study identified some of standard
parameters based on Indonesian Herbal Pharmacopeia that may be useful as guidelines to choose mindi
leaves for anti-cancer herbal.
1 INTRODUCTION
Mindi (Melia azedarach L.) is a plant species
belonging to the family Meliaceae, a Mahogany
family (Sapindales order). It is native to Asia but is
now found in parts of Northern Australia, Africa,
North America, tropical South America and
Southern Europe. In South America is commonly
known as paraiso or paradise, and in the US as
Indian lilac or white cedar. The leaves, fruits, bark
and root are use in traditional and medicine. The
leaves are used for in the traditional medical systems
of India (Ayurvedic, Unani-Tibb), China, Japan and
Taiwan as well. Leaves have been used as a natural
insecticide to keep with stored food, but highly
poisonous if eaten. It’s used traditionally as an
anthelmintic, diuretic, emmenagouge, expectorant,
vermifuge, piles, as astringent, in hysteria, leprosy,
and in scrofula. in Japan, have been used for
vermicide, anodyne, and skin disease, while in
Traditional Chinese Medicine, it is used as an anti-
parasitic and antifungal agent. It has been shown to
various pharmacological activities like antifungal,
anti-malarial, antibacterial, hepatoprotective, anti-
oxidant, anti-fertility, anthelmintic, antipyretic and
cytotoxic activities (Sultana, et al., 2014).
Therefore, it is necessary to standardization which
can affect quality of both extract and raw material by
method that have been established by Ministry of
Health through Indonesia Herbal Pharmacopeia. It is
a guarantee for safety, effectiveness, and especially
quality of plant material obtained, raw material that
will developed into phytopharmaca preparation
2 MATERIAL AND METHODS
2.1. Plant Material
In this research, the raw material were obtained from
Materia Medica Batu , East Java and taken already
in dried raw material.
Fig.1. Mindi Leaves (Melia azedarach L.)