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Authors: Ch. Wenger 1 ; X. Knigge 2 ; M. Fraschke 1 ; D. Wolansky 1 ; P. Kulse 1 ; U. Kaletta 1 ; A. Wolff 1 ; W. Mehr 1 ; E.-M. Laux 2 ; F. F. Bier 2 and R. Hölzel 2

Affiliations: 1 IHP GmbH – Leibniz Institute for Innovative Microelectronics, Germany ; 2 Fraunhofer Institute for Biomedical Engineering IBMT, Germany

Keyword(s): Dielectrophoresis, Nanoelectrodes, Biosensing.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Instruments and Devices ; Biomedical Sensors ; Hardware ; MEMS ; Microelectronics ; Nanotechnologies ; Sensor Networks

Abstract: Dielectrophoresis (DEP) is an established method for the spatial manipulation of microscopical particles. We demonstrate the temporal and permanent immobilization of polystyrene nanoparticles and protein molecules with sizes ranging from 4 nm to 500 nm. For this, regular arrays of silicon based nanoelectrodes were developed with tip diameters of 10 nm and 50 nm. No chemical modifications of molecules, particles or surfaces were needed. This opens up potentially important applications of DEP in biosensing and cell research.

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Paper citation in several formats:
Wenger, C.; Knigge, X.; Fraschke, M.; Wolansky, D.; Kulse, P.; Kaletta, U.; Wolff, A.; Mehr, W.; Laux, E.; Bier, F. and Hölzel, R. (2014). Label-free Immobilization of Nano-particles on Silicon based Electrodes for Single-biomolecule Studies. In Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2014) - BIODEVICES; ISBN 978-989-758-013-0; ISSN 2184-4305, SciTePress, pages 176-180. DOI: 10.5220/0004888101760180

@conference{biodevices14,
author={Ch. Wenger. and X. Knigge. and M. Fraschke. and D. Wolansky. and P. Kulse. and U. Kaletta. and A. Wolff. and W. Mehr. and E.{-}M. Laux. and F. F. Bier. and R. Hölzel.},
title={Label-free Immobilization of Nano-particles on Silicon based Electrodes for Single-biomolecule Studies},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2014) - BIODEVICES},
year={2014},
pages={176-180},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004888101760180},
isbn={978-989-758-013-0},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2014) - BIODEVICES
TI - Label-free Immobilization of Nano-particles on Silicon based Electrodes for Single-biomolecule Studies
SN - 978-989-758-013-0
IS - 2184-4305
AU - Wenger, C.
AU - Knigge, X.
AU - Fraschke, M.
AU - Wolansky, D.
AU - Kulse, P.
AU - Kaletta, U.
AU - Wolff, A.
AU - Mehr, W.
AU - Laux, E.
AU - Bier, F.
AU - Hölzel, R.
PY - 2014
SP - 176
EP - 180
DO - 10.5220/0004888101760180
PB - SciTePress