Authors:
Luis Martín
1
;
Alberto Anguita
1
;
Víctor Maojo
1
;
Erwin Bonsma
2
;
Anca Bucur
2
;
Jeroen Vrijnsen
2
;
Mathias Brochhausen
3
;
Christian Cocos
3
;
Holger Stenzhorn
3
;
Manolis Tsiknakis
4
;
Martin Doerr
4
and
Haridimos Kondylakis
4
Affiliations:
1
Biomedical Informatics Group, Artificial Intelligence Laboratory, School of Computer Science, Universidad Politécnica de Madrid, Spain
;
2
Phillips Research, Healthcare System Architecture, Netherlands
;
3
IFOMIS, Universität des Saarlandes, Germany
;
4
Institute of Computer Science Foundation for Research and Technology - Hellas, Greece
Keyword(s):
Ontology-based Biomedical Database Integration, Semantic Mediation, Ontologies, Post-genomic Clinical Trials, Service Oriented Architectures.
Related
Ontology
Subjects/Areas/Topics:
Affective Computing
;
Applications
;
Artificial Intelligence
;
Biomedical Engineering
;
Biomedical Signal Processing
;
Business Analytics
;
Cardiovascular Technologies
;
Cloud Computing
;
Cognitive Informatics
;
Collaboration and e-Services
;
Complex Systems Modeling and Simulation
;
Computing and Telecommunications in Cardiology
;
Confidentiality and Data Security
;
Data Engineering
;
Data Mining
;
Databases and Datawarehousing
;
Databases and Information Systems Integration
;
Datamining
;
Development of Assistive Technology
;
Devices
;
Distributed and Mobile Software Systems
;
e-Business
;
e-Commerce in the Health Sector
;
e-Health
;
Enterprise Information Systems
;
Expert Systems
;
Health Engineering and Technology Applications
;
Health Information Systems
;
Hospital Management Systems
;
Human-Computer Interaction
;
Human-Machine Interfaces for Disabled Persons
;
ICT for Cognitive Disabilities
;
ICT, Ageing and Disability
;
Integration/Interoperability
;
Interoperability
;
Knowledge Engineering and Ontology Development
;
Knowledge Management and Information Sharing
;
Knowledge-Based Systems
;
Medical and Nursing Informatics
;
Mobile Technologies
;
Mobile Technologies for Healthcare Applications
;
Neural Rehabilitation
;
Neurotechnology, Electronics and Informatics
;
Online Medical Applications
;
Ontologies and the Semantic Web
;
Physiological Computing Systems
;
Physiological Modeling
;
Platforms and Applications
;
Practice Based Research Methods for Assistive Technology
;
Semantic Interoperability
;
Sensor Networks
;
Signal Processing
;
Simulation and Modeling
;
Socio-Economic Issues of Assistive Technology
;
Soft Computing
;
Software Agents and Internet Computing
;
Software and Architectures
;
Software Engineering
;
Symbolic Systems
;
Telemedicine
;
Therapeutic Systems and Technologies
;
Wearable Sensors and Systems
Abstract:
In this work, we describe the set of tools comprising the Data Access Infrastructure within Advancing
Clinico-genomic Trials on Cancer (ACGT), a R&D Project funded in part by the European. This infrastructure aims at improving Post-genomic clinical trials by providing seamless access to integrated clinical, genetic, and image databases. A data access layer, based on OGSA-DAI, has been developed in order to cope with syntactic heterogeneities in databases. The semantic problems present in data sources with different nature are tackled by two core tools, namely the Semantic Mediator and the Master Ontology on Cancer. The ontology is used as a common framework for semantics, modelling the domain and acting as giving support to homogenization. SPARQL has been selected as query language for the Data Access Services and the Mediator. Two experiments have been carried out in order to test the suitability of the selected approach, integrating clinical and DICOM image databases.