Authors:
Tatsuya Kawaoka
1
;
2
;
3
;
Ryota Sakayama
3
;
Kousaku Ohta
2
and
Masatoshi Funabashi
1
;
2
;
3
Affiliations:
1
Kyoto University Research Division on Social Common Capital and the Future, Yoshidashimoadachicho 46 Inamori Center2F 228, Kyoto Sakyo-ku, Kyoto, Japan
;
2
Sony Computer Science Laboratories, Inc. Takanawa Muse Building 3F, Higashigotanda 3-14-13, Shinagawa-Ku, Tokyo, Japan
;
3
Synecoculture Association, Oiso 55, Oiso-Cho, Naka-gun, Kanagawa, Japan
Keyword(s):
Ecosystem Functions, Dementia, Health Tech, Immune-Related Diseases.
Abstract:
Immune-related diseases, such as allergies, asthma, and dementia, are rising globally, driven by aging populations and declining ecosystem functions. Traditional elementary reductionist approaches struggle to address the complex pathologies underlying these diseases. This study explores a personalized, ecosystem-based approach to mitigating immune dysregulation using a supportive ICT platform. We developed a data-driven analytical system that identifies individual metabolic challenges through the measurement of multiple biomarkers and clinical interviews, categorizing them into metabolic traits such as inflammatory, stress-related, and glucotoxic factors. Based on these assessments, professional staff provided tailored lifestyle advice and rehabilitation interventions, including light exercises in high biodiversity environments. The results showed significant improvements in cognitive and immune functions: Participants exhibited a 3.5-point average increase in MoCA scores over three
months, including functional recovery from Parkinson’s disease and CVA. Furthermore, the study identified phytochemical-rich foods, such as coarse green tea, as significant factors enhancing rehabilitation outcomes. These findings emphasize the importance of synergy between ecological environments and public health initiatives, aligning with the Planetary Health framework. By integrating multivariate analysis, personalized interventions, and ecosystem considerations through an integrative ICT platform, this approach offers a scalable solution to addressing immune-related diseases and reducing social security costs, with implications for global healthcare and environmental policies.
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