Authors:
T. Pereira
1
;
I. Santos
1
;
T. Oliveira
1
;
P. Vaz
1
;
T. Pereira
2
;
H. Santos
2
;
H. Pereira
3
;
V. Almeida
1
;
J. Cardoso
1
and
C. Correia
1
Affiliations:
1
University of Coimbra, Portugal
;
2
Coimbra College of Health Technology, Portugal
;
3
University of Coimbra and ISA- Intelligent Sensing Anywhere, Portugal
Keyword(s):
Optical Probe, Waveform Distension, Hemodynamic Parameters, Pulse Wave Velocity, Pulse Waveform Analysis.
Related
Ontology
Subjects/Areas/Topics:
Applications and Services
;
Biomedical Engineering
;
Biomedical Signal Processing
;
Cardiovascular Signals
;
Computer Vision, Visualization and Computer Graphics
;
Medical Image Detection, Acquisition, Analysis and Processing
Abstract:
Presently the interest in non-invasive devices for monitoring the cardiovascular system has increased in importance, especially in the diagnosis of some pathologies. The proposed optical device reveals an attractive instrumental solution for local pulse wave velocity (PWV) assessment and other hemodynamic parameters analysis, such as Augmentation Index (AIx), Subendocardial Viability Ratio (SEVR), Maximum Rate of Pressure Change (dP/dtmax) and Ejection Time Index (ETI). These parameters allow a better knowledge on the cardiovascular condition and management of many disease states. Two studies were performed in order to validate this technology. Firstly, a comparative test between the optical system and a gold-standard in PWV assessment was carried out. Afterwards, a large study was performed in 131 young subjects to establish carotid PWV reference values as well as other hemodynamic parameters and to find correlations between these and the population characteristics. The results allo
wed the use of this new technique as a reliable method to determine these parameters. For the total of subjects values for carotid PWV vary between 3-7.69 m s-1 a clear correlation with age and smoking status was found out. The Aix varies between -6.15% and 11.46% and exhibit a negative correlation with heart, and dP/dtmax parameter shows a significant decrease with age.
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