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Authors: Per-Olov Östberg 1 ; Andreas Hellander 2 ; Brian Drawert 3 ; Erik Elmroth 1 ; Sverker Holmgren 4 and Linda Petzold 3

Affiliations: 1 Umeå University, Sweden ; 2 Uppsala University and University of California, Sweden ; 3 University of California, United States ; 4 Uppsala University, Sweden

Keyword(s): Systems biology, eScience, Grid computing, Cloud computing, Service-oriented architecture.

Related Ontology Subjects/Areas/Topics: Algorithms and Software Tools ; Bioinformatics ; Biomedical Engineering ; Systems Biology

Abstract: Management of eScience computations and resulting data in distributed computing environments is complicated and often introduces considerable overhead. In this work we address a lack of integration tools that provide the abstraction levels, performance, and usability required to facilitate migration of eScience applications to distributed computing environments. In particular, we explore an approach to raising abstraction levels based on separation of computation design from computation management and present StratUm, a computation enactment tool for distributed computing environments. Results are illustrated in a case study of integration of a software from the systems biology community with a grid computation management system.

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Paper citation in several formats:
Östberg, P.; Hellander, A.; Drawert, B.; Elmroth, E.; Holmgren, S. and Petzold, L. (2012). ABSTRACTIONS FOR SCALING eSCIENCE APPLICATIONS TO DISTRIBUTED COMPUTING ENVIRONMENTS - A StratUm Integration Case Study in Molecular Systems Biology. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2012) - BIOINFORMATICS; ISBN 978-989-8425-90-4; ISSN 2184-4305, SciTePress, pages 290-294. DOI: 10.5220/0003765002900294

@conference{bioinformatics12,
author={Per{-}Olov Östberg. and Andreas Hellander. and Brian Drawert. and Erik Elmroth. and Sverker Holmgren. and Linda Petzold.},
title={ABSTRACTIONS FOR SCALING eSCIENCE APPLICATIONS TO DISTRIBUTED COMPUTING ENVIRONMENTS - A StratUm Integration Case Study in Molecular Systems Biology},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2012) - BIOINFORMATICS},
year={2012},
pages={290-294},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003765002900294},
isbn={978-989-8425-90-4},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2012) - BIOINFORMATICS
TI - ABSTRACTIONS FOR SCALING eSCIENCE APPLICATIONS TO DISTRIBUTED COMPUTING ENVIRONMENTS - A StratUm Integration Case Study in Molecular Systems Biology
SN - 978-989-8425-90-4
IS - 2184-4305
AU - Östberg, P.
AU - Hellander, A.
AU - Drawert, B.
AU - Elmroth, E.
AU - Holmgren, S.
AU - Petzold, L.
PY - 2012
SP - 290
EP - 294
DO - 10.5220/0003765002900294
PB - SciTePress