Authors:
L. Gonçalves
1
;
J. Novo
2
;
A. Cunha
3
and
A. Campilho
4
Affiliations:
1
INESC TEC - INESC Technology and Science, Portugal
;
2
University of A Coruña, Spain
;
3
INESC TEC - INESC Technology and Science and University of Tras-os-Montes and Alto Douro, Portugal
;
4
INESC TEC - INESC Technology and Science and Faculty of Engineering of the University of Porto, Portugal
Keyword(s):
Medical Diagnostic Imaging, Computer-aided Diagnosis, Computed Tomography, Machine Learning, Feature Extraction.
Related
Ontology
Subjects/Areas/Topics:
Applications and Services
;
Computer Vision, Visualization and Computer Graphics
;
Features Extraction
;
Image and Video Analysis
;
Medical Image Applications
Abstract:
In lung cancer diagnosis, the design of robust Computer Aided Diagnosis (CAD) systems needs to include an adequate differentiation of benign from malignant nodules. This paper presents a CAD system for the classification of lung nodules in chest Computed Tomography (CT) scans as the way to diagnose lung cancer. The proposed method measures a set of 295 heterogeneous characteristics, including morphology, intensity or texture features, that were used as input of different KNN and SVM classifiers.
The system was modeled and trained using a groundtruth provided by specialists taken from a public lung image dataset, the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI). This image dataset includes chest CT scans with lung nodule location together with information about the degree of malignancy, among other properties, provided by multiple expert clinicians. In particular, the computed degree of malignancy try to follow the manual labeling by the different
radiologists. Promising results were obtained with a first order SVM with an exponential kernel achieving an area under the receiver operating characteristic curve of 96.2 ± 0.5% when compared with the groundtruth provided in the public CT lung image dataset.
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