loading
Papers Papers/2022 Papers Papers/2022

Research.Publish.Connect.

Paper

Paper Unlock

Authors: Daniel Martin Martin Fernández 1 ; Pablo Pérez García 1 ; María E. Martín 2 ; Paula Daza 2 ; Juan Alfonso Serrano-Viseas 1 ; Gloria Huertas 1 and Alberto Yúfera 1

Affiliations: 1 Instituto de Microelectrónica de Sevilla (IMSE), Universidad de Sevilla, Av. Americo Vespuccio, S/N Sevilla, Spain ; 2 Departamento de Biología Celular, Facultad de Biología, Universidad de Sevilla, Av. Reina Mercedes, S/N, Sevilla, Spain

Keyword(s): Biomedical Circuits, Electrical Pulse Stimulation (EPS), Microelectrodes, Neuroblastoma (N2A), Stem Cell Differentiation.

Abstract: This work describes Electrical Stimulations (ES) assays on stem cells. The neuroblastoma (N2A) cell linage was submitted to several electrical fields to enable and enhance its differentiation toward neurons. Both Direct Current (DC) and Alternated Current (AC) time dependent electric field protocols were applied to N2A cell culture under differentiation conditions, obtaining different responses. Control and electrically excited samples’ number of differentiated cells and neurite lengths were measure after differentiation. Results showed that DC fields have a strong influence on N2A differentiation since the percentage of differentiated cells and the neurites lengths were the highest. In addition, a significant alignment of neurites measured with the applied electrical field has been detected, which demonstrates the high sensitivity of differentiation processes to electrical field polarity.

CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 3.144.42.196

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Martin Fernández, D.; García, P.; Martín, M.; Daza, P.; Serrano-Viseas, J.; Huertas, G. and Yúfera, A. (2021). Effects of Electrical Fields on Neuroblastoma (N2A) Cell Differentiation: Preliminary Results. In Proceedings of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2021) - BIODEVICES; ISBN 978-989-758-490-9; ISSN 2184-4305, SciTePress, pages 152-159. DOI: 10.5220/0010320100002865

@conference{biodevices21,
author={Daniel Martin {Martin Fernández}. and Pablo Pérez García. and María E. Martín. and Paula Daza. and Juan Alfonso Serrano{-}Viseas. and Gloria Huertas. and Alberto Yúfera.},
title={Effects of Electrical Fields on Neuroblastoma (N2A) Cell Differentiation: Preliminary Results},
booktitle={Proceedings of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2021) - BIODEVICES},
year={2021},
pages={152-159},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010320100002865},
isbn={978-989-758-490-9},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2021) - BIODEVICES
TI - Effects of Electrical Fields on Neuroblastoma (N2A) Cell Differentiation: Preliminary Results
SN - 978-989-758-490-9
IS - 2184-4305
AU - Martin Fernández, D.
AU - García, P.
AU - Martín, M.
AU - Daza, P.
AU - Serrano-Viseas, J.
AU - Huertas, G.
AU - Yúfera, A.
PY - 2021
SP - 152
EP - 159
DO - 10.5220/0010320100002865
PB - SciTePress

- Science and Technology Publications, Lda.
RESOURCES

Proceedings

Papers

Authors

Ontology

CONTACTS

Science and Technology Publications, Lda
Avenida de S. Francisco Xavier, Lote 7 Cv. C,
2900-616 Setúbal, Portugal.

Phone: +351 265 520 185 (National fixed network call)
Fax: +351 265 520 186
Email: info@scitepress.org

EXTERNAL LINKS

PRIMORIS

INSTICC

SCITEVENTS

CROSSREF

PROCEEDINGS SUBMITTED FOR INDEXATION BY:

dblp

Ei Compendex

SCOPUS

Semantic Scholar

Google Scholar

Microsoft Academic