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Authors: D. S. Ferreira 1 ; N. Lue 2 ; G. Minas 1 ; K. Badizadegan 3 ; M. S. Feld 2 and C. Yu 4

Affiliations: 1 Universidade do Minho, Portugal ; 2 Massachusetts Institute of Technology, United States ; 3 Harvard Medical School and Massachusetts General Hospital, United States ; 4 Canon U.S.A. and Inc., United States

Keyword(s): Spectroscopic scanner, Diffuse reflectance, Fluorescence, Spectral imaging.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Equipment ; Biomedical Instrumentation ; Biomedical Instruments and Devices

Abstract: We describe an ex vivo quantitative spectroscopy (QS) scanning platform which enables integration of different optical modalities for the assessment of ex vivo tissue properties. As a first implementation, the QS scanner combines diffuse reflectance spectroscopy (DRS) and intrinsic fluorescence spectroscopy (IFS) to provide a multidimensional image of tissue structural and biochemical properties. The wide area coverage is achieved by mechanically scanning of the optical probe. The spectroscopic data is taken one grid at a time with variable grid-to-grid (GTG) distance and field of view (FOV). The ex vivo tissue surface under examination can have a variable size since both GTG distance and FOV can be controlled. We demonstrate the clinical utility of this system using an ex vivo tissue model with ultimate goal of imaging excised tissue margins.

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Paper citation in several formats:
S. Ferreira, D.; Lue, N.; Minas, G.; Badizadegan, K.; S. Feld, M. and Yu, C. (2012). DEVELOPMENT OF AN EX VIVO QUANTITATIVE SPECTROSCOPIC SCANNER. In Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2012) - BIODEVICES; ISBN 978-989-8425-91-1; ISSN 2184-4305, SciTePress, pages 274-279. DOI: 10.5220/0003888402740279

@conference{biodevices12,
author={D. {S. Ferreira}. and N. Lue. and G. Minas. and K. Badizadegan. and M. {S. Feld}. and C. Yu.},
title={DEVELOPMENT OF AN EX VIVO QUANTITATIVE SPECTROSCOPIC SCANNER},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2012) - BIODEVICES},
year={2012},
pages={274-279},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003888402740279},
isbn={978-989-8425-91-1},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2012) - BIODEVICES
TI - DEVELOPMENT OF AN EX VIVO QUANTITATIVE SPECTROSCOPIC SCANNER
SN - 978-989-8425-91-1
IS - 2184-4305
AU - S. Ferreira, D.
AU - Lue, N.
AU - Minas, G.
AU - Badizadegan, K.
AU - S. Feld, M.
AU - Yu, C.
PY - 2012
SP - 274
EP - 279
DO - 10.5220/0003888402740279
PB - SciTePress

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