microRNA detection with an active nanodevice FoF1-ATPase

Yao-Gen Shu; Zhong-Can Ou-Yang

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Paper

microRNA detection with an active nanodevice FoF1-ATPase

Topics: Biomaterials; Biomechanical Devices; Biomedical Metrology; Biomedical Sensors

In Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIOSTEC, 166-169, 2016 , Rome, Italy

Authors: Yao-Gen Shu and Zhong-Can Ou-Yang

Affiliation: Institute of Theoretical Physics and Chinese Academy of Sciences, China

Keyword(s): microRNA detection, rotary motor, chromatophore

Related Ontology Subjects/Areas/Topics: Biomaterials ; Biomechanical Devices ; Biomedical Engineering ; Biomedical Instruments and Devices ; Biomedical Metrology ; Biomedical Sensors

Abstract: We have developed a novel nanodevice constituted with a rotary motor and a ``battery'', FoF1-ATPase and chromatophore. The latter can be recharged enough energy by light so that the former can rotates at about 1000 r.p.m for more than one hour. If the nanodevice is captured by a target such as miRNA and processively rotate for 30 minutes, the number of targets will be amplified by 100000 ATP molecules. This method has potential to be developed into an ultrasensitive biosensor to detect low expressed targets such as miRNA.

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Paper citation in several formats:

Shu, Y. and Ou-Yang, Z. (2016). microRNA detection with an active nanodevice FoF1-ATPase. In Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2016) - BIODEVICES; ISBN 978-989-758-170-0; ISSN 2184-4305, SciTePress, pages 166-169. DOI: 10.5220/0005692301660169

@conference{biodevices16,
author={Yao{-}Gen Shu. and Zhong{-}Can Ou{-}Yang.},
title={microRNA detection with an active nanodevice FoF1-ATPase},
booktitle={Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2016) - BIODEVICES},
year={2016},
pages={166-169},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005692301660169},
isbn={978-989-758-170-0},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2016) - BIODEVICES
TI - microRNA detection with an active nanodevice FoF1-ATPase
SN - 978-989-758-170-0
IS - 2184-4305
AU - Shu, Y.
AU - Ou-Yang, Z.
PY - 2016
SP - 166
EP - 169
DO - 10.5220/0005692301660169
PB - SciTePress