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Authors: Hussein Mehidine 1 ; Fanny Poulon 2 ; Ali Ibrahim 2 ; Marjorie Juchaux 2 ; Pascale Varlet 3 ; Bertrand Devaux 4 ; Johan Pallud 5 and Darine Abi Haidar 1

Affiliations: 1 Paris-Saclay University and Université Paris Diderot, France ; 2 Paris-Saclay University, France ; 3 Sainte-Anne Hospital and Centre de Psychiatrie et de Neurosciences, France ; 4 Sainte-Anne Hospital, France ; 5 Centre de Psychiatrie et de Neurosciences and Sainte-Anne Hospital, France

Keyword(s): Glioblastoma, Scattering Coefficient, Absorption Coefficient, Endogenous Fluorescence.

Related Ontology Subjects/Areas/Topics: Biomedical Optics ; Optics ; Photonics, Optics and Laser Technology

Abstract: Survival rates and health-related quality of life of adult patients suffering from glioblastoma depend significantly on the extent (no residual tumor tissue) and precision (no collateral damage) of the surgical resection. Assistance in defining the borders of the infiltrating component of the glioblastoma would be valuable to improve outcomes. A tissue can be defined by its optical properties : absorption, scattering, intensity of fluorescence, that will give a unique signature. In this work we look at the absorption and scattering coefficients of glioblastoma and control tissues from adult patients using an integrating sphere, spectral measurements were also took on the samples using a fiber endoscope. The preliminary results show the potential of using endogenous fluorescence for intraoperative identification of residual glioblastoma tissue in the wall of the surgical cavity of resection.

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Paper citation in several formats:
Mehidine, H.; Poulon, F.; Ibrahim, A.; Juchaux, M.; Varlet, P.; Devaux, B.; Pallud, J. and Abi Haidar, D. (2018). Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties. In Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS; ISBN 978-989-758-286-8; ISSN 2184-4364, SciTePress, pages 136-140. DOI: 10.5220/0006531501360140

@conference{photoptics18,
author={Hussein Mehidine. and Fanny Poulon. and Ali Ibrahim. and Marjorie Juchaux. and Pascale Varlet. and Bertrand Devaux. and Johan Pallud. and Darine {Abi Haidar}.},
title={Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties},
booktitle={Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS},
year={2018},
pages={136-140},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006531501360140},
isbn={978-989-758-286-8},
issn={2184-4364},
}

TY - CONF

JO - Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS
TI - Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties
SN - 978-989-758-286-8
IS - 2184-4364
AU - Mehidine, H.
AU - Poulon, F.
AU - Ibrahim, A.
AU - Juchaux, M.
AU - Varlet, P.
AU - Devaux, B.
AU - Pallud, J.
AU - Abi Haidar, D.
PY - 2018
SP - 136
EP - 140
DO - 10.5220/0006531501360140
PB - SciTePress

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