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Authors: Giulia Menconi 1 ; Giovanni Battaglia 2 ; Roberto Grossi 2 ; Nadia Pisanti 2 and Roberto Marangoni 3

Affiliations: 1 Istituto Nazionale di Alta Matematica, Italy ; 2 Universitá di Pisa, Italy ; 3 Universitá di Pisa and CNR, Italy

Keyword(s): Mobile elements, Multiple genome comparison.

Related Ontology Subjects/Areas/Topics: Algorithms and Software Tools ; Bioinformatics ; Biomedical Engineering ; Genomics and Proteomics ; Sequence Analysis

Abstract: Mobilomics calls for detecting all the mobile elements in a genome so as to understand their dynamic behavior. We devise and apply a method that extends a pairwise strain comparison tool for mobile genetic elements (MGE) inference, and perform experiments on a whole dataset of 39 complete genomes of as many yeast (S.cerevisiae) strains. We locate a priori all the MGEs regions that are annotated in the reference sequence at hand, and map all the putative MGEs in all the other (non-annotated) strains. Interestingly, evolutionary relation among the strains based on the presence/absence of candidate MGEs, turns out to be quite close to that inferred by classic phylogenetic methods based on SNPs analysis.

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Paper citation in several formats:
Menconi, G.; Battaglia, G.; Grossi, R.; Pisanti, N. and Marangoni, R. (2012). A TASTE OF YEAST MOBILOMICS. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2012) - BIOINFORMATICS; ISBN 978-989-8425-90-4; ISSN 2184-4305, SciTePress, pages 271-274. DOI: 10.5220/0003702302710274

@conference{bioinformatics12,
author={Giulia Menconi. and Giovanni Battaglia. and Roberto Grossi. and Nadia Pisanti. and Roberto Marangoni.},
title={A TASTE OF YEAST MOBILOMICS},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2012) - BIOINFORMATICS},
year={2012},
pages={271-274},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003702302710274},
isbn={978-989-8425-90-4},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2012) - BIOINFORMATICS
TI - A TASTE OF YEAST MOBILOMICS
SN - 978-989-8425-90-4
IS - 2184-4305
AU - Menconi, G.
AU - Battaglia, G.
AU - Grossi, R.
AU - Pisanti, N.
AU - Marangoni, R.
PY - 2012
SP - 271
EP - 274
DO - 10.5220/0003702302710274
PB - SciTePress